Costs of distributing HIV self-testing kits in Eswatini through community and workplace models.


Journal

BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551

Informations de publication

Date de publication:
29 Feb 2024
Historique:
received: 02 05 2021
accepted: 10 10 2023
medline: 4 3 2024
pubmed: 1 3 2024
entrez: 29 2 2024
Statut: epublish

Résumé

This study evaluates the implementation and running costs of an HIV self-testing (HIVST) distribution program in Eswatini. HIVST kits were delivered through community-based and workplace models using primary and secondary distribution. Primary clients could self-test onsite or offsite. This study presents total running economic costs of kit distribution per model between April 2019 and March 2020, and estimates average cost per HIVST kit distributed, per client self-tested, per client self-tested reactive, per client confirmed positive, and per client initiating antiretroviral therapy (ART). Distribution data and follow-up phone interviews were analysed to estimate implementation outcomes. Results were presented for each step of the care cascade using best-case and worst-case scenarios. A top-down incremental cost-analysis was conducted from the provider perspective using project expenditures. Sensitivity and scenario analyses explored effects of economic and epidemiological parameters on average costs. Nineteen thousand one hundred fifty-five HIVST kits were distributed to 13,031 individuals over a 12-month period, averaging 1.5 kits per recipient. 83% and 17% of kits were distributed via the community and workplace models, respectively. Clients reached via the workplace model were less likely to opt for onsite testing than clients in the community model (8% vs 29%). 6% of onsite workplace testers tested reactive compared to 2% of onsite community testers. Best-case scenario estimated 17,458 (91%) clients self-tested, 633 (4%) received reactive-test results, 606 (96%) linked to confirmatory testing, and 505 (83%) initiated ART. Personnel and HIVST kits represented 60% and 32% of total costs, respectively. Average costs were: per kit distributed US$17.23, per client tested US$18.91, per client with a reactive test US$521.54, per client confirmed positive US$550.83, and per client initiating ART US$708.60. Lower rates for testing, reactivity, and linkage to care in the worst-case scenario resulted in higher average costs along the treatment cascade. This study fills a significant evidence gap regarding costs of HIVST provision along the client care cascade in Eswatini. Workplace and community-based distribution of HIVST accompanied with effective linkage to care strategies can support countries to reach cascade objectives.

Sections du résumé

BACKGROUND BACKGROUND
This study evaluates the implementation and running costs of an HIV self-testing (HIVST) distribution program in Eswatini. HIVST kits were delivered through community-based and workplace models using primary and secondary distribution. Primary clients could self-test onsite or offsite. This study presents total running economic costs of kit distribution per model between April 2019 and March 2020, and estimates average cost per HIVST kit distributed, per client self-tested, per client self-tested reactive, per client confirmed positive, and per client initiating antiretroviral therapy (ART).
METHODS METHODS
Distribution data and follow-up phone interviews were analysed to estimate implementation outcomes. Results were presented for each step of the care cascade using best-case and worst-case scenarios. A top-down incremental cost-analysis was conducted from the provider perspective using project expenditures. Sensitivity and scenario analyses explored effects of economic and epidemiological parameters on average costs.
RESULTS RESULTS
Nineteen thousand one hundred fifty-five HIVST kits were distributed to 13,031 individuals over a 12-month period, averaging 1.5 kits per recipient. 83% and 17% of kits were distributed via the community and workplace models, respectively. Clients reached via the workplace model were less likely to opt for onsite testing than clients in the community model (8% vs 29%). 6% of onsite workplace testers tested reactive compared to 2% of onsite community testers. Best-case scenario estimated 17,458 (91%) clients self-tested, 633 (4%) received reactive-test results, 606 (96%) linked to confirmatory testing, and 505 (83%) initiated ART. Personnel and HIVST kits represented 60% and 32% of total costs, respectively. Average costs were: per kit distributed US$17.23, per client tested US$18.91, per client with a reactive test US$521.54, per client confirmed positive US$550.83, and per client initiating ART US$708.60. Lower rates for testing, reactivity, and linkage to care in the worst-case scenario resulted in higher average costs along the treatment cascade.
CONCLUSION CONCLUSIONS
This study fills a significant evidence gap regarding costs of HIVST provision along the client care cascade in Eswatini. Workplace and community-based distribution of HIVST accompanied with effective linkage to care strategies can support countries to reach cascade objectives.

Identifiants

pubmed: 38424538
doi: 10.1186/s12879-023-08694-y
pii: 10.1186/s12879-023-08694-y
pmc: PMC10902928
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

976

Subventions

Organisme : World Health Organization
ID : 001
Pays : International

Informations de copyright

© 2024. The Author(s).

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Auteurs

Kathleen McGee (K)

Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK. kat.v.mcgee@gmail.com.

Marc d'Elbée (M)

Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.

Ralitza Dekova (R)

Population Services International, Mbabane, Eswatini.

Linda A Sande (LA)

Malawi Liverpool Wellcome Trust Research Programme, Blantyre, Malawi.

Lenhle Dube (L)

Ministry of Health, Mbabane, Eswatini.

Sanele Masuku (S)

Population Services International, Mbabane, Eswatini.

Makhosazana Dlamini (M)

Population Services International, Mbabane, Eswatini.

Collin Mangenah (C)

Centre for Sexual Health and HIV/AIDS Research, Harare, Zimbabwe.

Lawrence Mwenge (L)

Zambart, Lusaka, Zambia.

Cheryl Johnson (C)

World Health Organisation, Global HIV, Hepatitis and STI Programmes, Geneva, Switzerland.

Karin Hatzold (K)

Population Services International, Cape Town, South Africa.

Melissa Neuman (M)

Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

Gesine Meyer-Rath (G)

Center for Global Heath and Development, Boston University School of Public Health, Boston, USA.
Health Economics and Epidemiology Research Office, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Fern Terris-Prestholt (F)

Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.

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Classifications MeSH