Temporally organized representations of reward and risk in the human brain.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
09 Mar 2024
09 Mar 2024
Historique:
received:
08
05
2023
accepted:
13
02
2024
medline:
11
3
2024
pubmed:
10
3
2024
entrez:
9
3
2024
Statut:
epublish
Résumé
The value and uncertainty associated with choice alternatives constitute critical features relevant for decisions. However, the manner in which reward and risk representations are temporally organized in the brain remains elusive. Here we leverage the spatiotemporal precision of intracranial electroencephalography, along with a simple card game designed to elicit the unfolding computation of a set of reward and risk variables, to uncover this temporal organization. Reward outcome representations across wide-spread regions follow a sequential order along the anteroposterior axis of the brain. In contrast, expected value can be decoded from multiple regions at the same time, and error signals in both reward and risk domains reflect a mixture of sequential and parallel encoding. We further highlight the role of the anterior insula in generalizing between reward prediction error and risk prediction error codes. Together our results emphasize the importance of neural dynamics for understanding value-based decisions under uncertainty.
Identifiants
pubmed: 38461343
doi: 10.1038/s41467-024-46094-1
pii: 10.1038/s41467-024-46094-1
pmc: PMC10924934
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2162Subventions
Organisme : NIMH NIH HHS
ID : R01 MH111425
Pays : United States
Commentaires et corrections
Type : UpdateOf
Informations de copyright
© 2024. The Author(s).
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