Tetrahedral framework nucleic acids for improving wound healing.
DNA nanomaterials
Tetrahedral framework nucleic acids
Tissue regeneration
Wound healing
Journal
Journal of nanobiotechnology
ISSN: 1477-3155
Titre abrégé: J Nanobiotechnology
Pays: England
ID NLM: 101152208
Informations de publication
Date de publication:
16 Mar 2024
16 Mar 2024
Historique:
received:
08
11
2023
accepted:
21
02
2024
medline:
18
3
2024
pubmed:
16
3
2024
entrez:
16
3
2024
Statut:
epublish
Résumé
Wounds are one of the most common health issues, and the cost of wound care and healing has continued to increase over the past decade. In recent years, there has been growing interest in developing innovative strategies to enhance the efficacy of wound healing. Tetrahedral framework nucleic acids (tFNAs) have emerged as a promising tool for wound healing applications due to their unique structural and functional properties. Therefore, it is of great significance to summarize the applications of tFNAs for wound healing. This review article provides a comprehensive overview of the potential of tFNAs as a novel therapeutic approach for wound healing. In this review, we discuss the possible mechanisms of tFNAs in wound healing and highlight the role of tFNAs in modulating key processes involved in wound healing, such as cell proliferation and migration, angiogenesis, and tissue regeneration. The targeted delivery and controlled release capabilities of tFNAs offer advantages in terms of localized and sustained delivery of therapeutic agents to the wound site. In addition, the latest research progress on tFNAs in wound healing is systematically introduced. We also discuss the biocompatibility and biosafety of tFNAs, along with their potential applications and future directions for research. Finally, the current challenges and prospects of tFNAs are briefly discussed to promote wider applications.
Identifiants
pubmed: 38491372
doi: 10.1186/s12951-024-02365-z
pii: 10.1186/s12951-024-02365-z
doi:
Substances chimiques
Nucleic Acids
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
113Subventions
Organisme : National Natural Science Foundation of China
ID : 82173808
Organisme : National Natural Science Foundation of China
ID : 82003710
Organisme : Natural Science Foundation of Guangdong Province
ID : 2021B1515020100
Informations de copyright
© 2024. The Author(s).
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