Lung repair and regeneration: Advanced models and insights into human disease.
lung
regeneration
stem cells
Journal
Cell stem cell
ISSN: 1875-9777
Titre abrégé: Cell Stem Cell
Pays: United States
ID NLM: 101311472
Informations de publication
Date de publication:
11 Mar 2024
11 Mar 2024
Historique:
received:
05
12
2023
revised:
07
02
2024
accepted:
22
02
2024
medline:
17
3
2024
pubmed:
17
3
2024
entrez:
16
3
2024
Statut:
aheadofprint
Résumé
The respiratory system acts as both the primary site of gas exchange and an important sensor and barrier to the external environment. The increase in incidences of respiratory disease over the past decades has highlighted the importance of developing improved therapeutic approaches. This review will summarize recent research on the cellular complexity of the mammalian respiratory system with a focus on gas exchange and immunological defense functions of the lung. Different models of repair and regeneration will be discussed to help interpret human and animal data and spur the investigation of models and assays for future drug development.
Identifiants
pubmed: 38492572
pii: S1934-5909(24)00052-3
doi: 10.1016/j.stem.2024.02.009
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests The authors declare no competing interests.