MmcA is an electron conduit that facilitates both intracellular and extracellular electron transport in Methanosarcina acetivorans.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
17 Apr 2024
Historique:
received: 22 08 2023
accepted: 05 04 2024
medline: 19 4 2024
pubmed: 18 4 2024
entrez: 17 4 2024
Statut: epublish

Résumé

Methanogens are a diverse group of Archaea that obligately couple energy conservation to the production of methane. Some methanogens encode alternate pathways for energy conservation, like anaerobic respiration, but the biochemical details of this process are unknown. We show that a multiheme c-type cytochrome called MmcA from Methanosarcina acetivorans is important for intracellular electron transport during methanogenesis and can also reduce extracellular electron acceptors like soluble Fe

Identifiants

pubmed: 38632227
doi: 10.1038/s41467-024-47564-2
pii: 10.1038/s41467-024-47564-2
pmc: PMC11024163
doi:

Substances chimiques

Cytochromes 0
Methane OP0UW79H66

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3300

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM136294
Pays : United States

Informations de copyright

© 2024. The Author(s).

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Auteurs

Dinesh Gupta (D)

Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.

Keying Chen (K)

Department of Chemistry, Boston University, Boston, MA, USA.

Sean J Elliott (SJ)

Department of Chemistry, Boston University, Boston, MA, USA.

Dipti D Nayak (DD)

Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA. dnayak@berkeley.edu.

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Classifications MeSH