Serum peripheral markers for inflammation in adolescents with anorexia nervosa.
Anorexia nervosa
adolescent
complete blood count
inflammation
platelet
Journal
International journal of psychiatry in clinical practice
ISSN: 1471-1788
Titre abrégé: Int J Psychiatry Clin Pract
Pays: England
ID NLM: 9709509
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
medline:
4
5
2024
pubmed:
23
4
2024
entrez:
22
4
2024
Statut:
ppublish
Résumé
There is a limited number of studies comparing the levels of inflammation in adolescent patients with anorexia nervosa (AN) and healthy controls based on complete blood count and platelet parameters. This study is a retrospective cross-sectional analysis of 53 drug-naive patients with AN and 53 healthy controls. Significant differences were observed for WBC (white blood cell), neutrophil, MCV (mean corpuscular volume), MCH (mean corpuscular haemoglobin) and neutrophils/lymphocytes ratio (NLR) between the study groups. Patients with AN had lower WBC, neutrophiles and NLR values. But there was no difference between the groups in terms of inflammation-related platelet parameters. A strong positive correlation between BMI (body mass index) and PLT (platelet), PCT (plateletcrit) was determined in the patient group ( The present study provides further evidence for level of inflammation in these patients does not increase during the acute period, unlike other mental diseases.
Sections du résumé
BACKGROUND
UNASSIGNED
There is a limited number of studies comparing the levels of inflammation in adolescent patients with anorexia nervosa (AN) and healthy controls based on complete blood count and platelet parameters.
METHODS
UNASSIGNED
This study is a retrospective cross-sectional analysis of 53 drug-naive patients with AN and 53 healthy controls.
RESULTS
UNASSIGNED
Significant differences were observed for WBC (white blood cell), neutrophil, MCV (mean corpuscular volume), MCH (mean corpuscular haemoglobin) and neutrophils/lymphocytes ratio (NLR) between the study groups. Patients with AN had lower WBC, neutrophiles and NLR values. But there was no difference between the groups in terms of inflammation-related platelet parameters. A strong positive correlation between BMI (body mass index) and PLT (platelet), PCT (plateletcrit) was determined in the patient group (
CONCLUSIONS
UNASSIGNED
The present study provides further evidence for level of inflammation in these patients does not increase during the acute period, unlike other mental diseases.
Identifiants
pubmed: 38648398
doi: 10.1080/13651501.2024.2343482
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM