Antitumoral Activity of the Universal Methyl Donor
Humans
Glioblastoma
/ drug therapy
S-Adenosylmethionine
/ pharmacology
Cell Line, Tumor
Apoptosis
/ drug effects
Cell Proliferation
/ drug effects
Antineoplastic Agents
/ pharmacology
Cell Survival
/ drug effects
DNA Repair
/ drug effects
Aurora Kinase B
/ metabolism
Brain Neoplasms
/ drug therapy
Rad51 Recombinase
/ metabolism
Cell Cycle Checkpoints
/ drug effects
Mitosis
/ drug effects
DNA damage response
S-Adenosylmethionine
cell cycle arrest and apoptosis
glioblastoma
homologous recombination repair
mitotic catastrophe
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
10 Apr 2024
10 Apr 2024
Historique:
received:
04
03
2024
revised:
03
04
2024
accepted:
04
04
2024
medline:
27
4
2024
pubmed:
27
4
2024
entrez:
27
4
2024
Statut:
epublish
Résumé
Glioblastoma (GBM), the most frequent and lethal brain cancer in adults, is characterized by short survival times and high mortality rates. Due to the resistance of GBM cells to conventional therapeutic treatments, scientific interest is focusing on the search for alternative and efficient adjuvant treatments.
Identifiants
pubmed: 38675528
pii: molecules29081708
doi: 10.3390/molecules29081708
pii:
doi:
Substances chimiques
S-Adenosylmethionine
7LP2MPO46S
Antineoplastic Agents
0
Aurora Kinase B
EC 2.7.11.1
Rad51 Recombinase
EC 2.7.7.-
AURKB protein, human
EC 2.7.11.1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM