Normal Puberty.
Follicle-stimulating hormone
Gonadarche
Gonadotropin-releasing hormone
Kisspeptin-neurokinin B-dynorphin neurons
Luteinizing hormone
Puberty
Journal
Endocrinology and metabolism clinics of North America
ISSN: 1558-4410
Titre abrégé: Endocrinol Metab Clin North Am
Pays: United States
ID NLM: 8800104
Informations de publication
Date de publication:
Jun 2024
Jun 2024
Historique:
medline:
28
4
2024
pubmed:
28
4
2024
entrez:
27
4
2024
Statut:
ppublish
Résumé
Puberty is characterized by gonadarche and adrenarche. Gonadarche represents the reactivation of the hypothalamic-pituitary-gonadal axis with increased gonadotropin-releasing hormone, luteinizing hormone, and follicle-stimulating hormone secretion following the quiescence during childhood. Pubarche is the development of pubic hair, axillary hair, apocrine odor reflecting the onset of pubertal adrenal maturation known as adrenarche. A detailed understanding of these pubertal processes will help clarify relationships between the timing of the onset of puberty and cardiovascular, metabolic, and reproductive outcomes in adulthood. The onset of gonadarche is influenced by neuroendocrine signals, genetic variants, metabolic factors, and environmental elements.
Identifiants
pubmed: 38677861
pii: S0889-8529(24)00003-3
doi: 10.1016/j.ecl.2024.01.001
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
183-194Informations de copyright
Copyright © 2024 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure The authors have nothing to disclose.