Exchangeable leaders of collectively migrating glioma abuse N-cadherin trafficking.

Cadherins / metabolism Humans Glioma / metabolism Cell Movement YAP-Signaling Proteins / metabolism Transcription Factors / metabolism Adaptor Proteins, Signal Transducing / metabolism Protein Transport Antigens, CD / metabolism

Journal

The Journal of cell biology
ISSN: 1540-8140
Titre abrégé: J Cell Biol
Pays: United States
ID NLM: 0375356

Informations de publication

Date de publication:
03 Jun 2024
Historique:
medline: 3 5 2024
pubmed: 3 5 2024
entrez: 3 5 2024
Statut: ppublish

Résumé

Collectively migrating cells consist of leaders and followers with different features. In this issue, Kim et al. (https://doi.org/10.1083/jcb.202401057) characterize the leader and follower cells in collective glioma migration and uncover important roles of YAP1/TAZ-mediated regulation of N-cadherin in the leader cells.

Identifiants

DOI: 10.1083/jcb.202404129 PMID: 38700903
pubmed: 38700903
pii: 276727
doi: 10.1083/jcb.202404129
pii:
doi:

Substances chimiques

Cadherins 0
YAP-Signaling Proteins 0
YAP1 protein, human 0
Transcription Factors 0
Adaptor Proteins, Signal Transducing 0
Antigens, CD 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Japan Society for the Promotion of Science
Organisme : Meiji Holdings Co., Ltd
Organisme : Takeda Science Foundation
Organisme : Institute for Molecular and Cellular Regulation, Gunma University

Informations de copyright

© 2024 Kawauchi and Ito.

Auteurs

Takeshi Kawauchi (T)

Department of Adaptive and Maladaptive Responses in Health and Disease, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
ORCID: 0000-0002-8650-4474

Shiho Ito (S)

Department of Adaptive and Maladaptive Responses in Health and Disease, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Cadhérines › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Gliome › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Phénomènes physiologiques › Mouvement cellulaire › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › Protéines de signalisation YAP › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Métabolisme › Transport biologique › Transport des protéines › Exchangeable leaders of collectively migrating...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Antigènes de différenciation › Antigènes CD › Exchangeable leaders of collectively migrating...