Systems Biology for Drug Target Discovery in Acute Myeloid Leukemia.

Humans Leukemia, Myeloid, Acute / drug therapy Tretinoin / pharmacology Systems Biology / methods HL-60 Cells Gene Expression Profiling K562 Cells Drug Discovery / methods Transcriptome Cell Line, Tumor Cyclin-Dependent Kinase 6 / metabolism Antineoplastic Agents / pharmacology Gene Expression Regulation, Leukemic / drug effects Tumor Necrosis Factor-alpha / metabolism
HL-60 K562 NB4 acute myeloid leukemia all-trans-retinoic acid granulocytic differentiation proteome transcriptome

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
23 Apr 2024
Historique:
received: 27 03 2024
revised: 18 04 2024
accepted: 20 04 2024
medline: 11 5 2024
pubmed: 11 5 2024
entrez: 11 5 2024
Statut: epublish

Résumé

Combining new therapeutics with all-

Identifiants

DOI: 10.3390/ijms25094618 PMID: 38731835
pubmed: 38731835
pii: ijms25094618
doi: 10.3390/ijms25094618
pii:
doi:

Substances chimiques

Tretinoin 5688UTC01R
Cyclin-Dependent Kinase 6 EC 2.7.11.22
Antineoplastic Agents 0
Tumor Necrosis Factor-alpha 0
CDK6 protein, human EC 2.7.11.22

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Russian Science Foundation
ID : 21-74-20122

Auteurs

Svetlana Novikova (S)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
ORCID: 0000-0003-2777-2476

Tatiana Tolstova (T)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
ORCID: 0000-0001-9053-6551

Leonid Kurbatov (L)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
ORCID: 0000-0002-8859-0118

Tatiana Farafonova (T)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
ORCID: 0000-0002-7633-3034

Olga Tikhonova (O)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.

Natalia Soloveva (N)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
ORCID: 0000-0002-8940-1454

Alexander Rusanov (A)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.

Victor Zgoda (V)

Institute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
ORCID: 0000-0002-4532-4274

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Leucémies › Leucémie myéloïde › Leucémie aigüe myéloïde › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Facteurs biologiques › Pigments biologiques › Caroténoïdes › Rétinoïdes › Trétinoïne › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Disciplines des sciences naturelles › Disciplines des sciences biologiques › Biologie › Biologie des systèmes › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Cellules › Cellules myéloïdes › Cellules HL-60 › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Cellules › Cellules érythroïdes › Cellules K562 › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Transcriptome › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Proline-directed protein kinases › Kinases cyclines-dépendantes › Kinase-6 cycline-dépendante › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes tumoraux › Régulation de l'expression des gènes dans la leucémie › Systems Biology for Drug Target Discovery in...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Facteurs de nécrose tumorale › Facteur de nécrose tumorale alpha › Systems Biology for Drug Target Discovery in...