Dopamine as a potential diagnostic biomarker in women's sexual dysfunction.
Humans
Female
Dopamine
/ blood
Biomarkers
/ blood
Adult
Sexual Dysfunction, Physiological
/ blood
Prolactin
/ blood
Progesterone
/ blood
Estradiol
/ blood
Case-Control Studies
Egypt
Sensitivity and Specificity
Surveys and Questionnaires
Young Adult
Middle Aged
Dehydroepiandrosterone
/ blood
Gonadal Steroid Hormones
/ blood
Dopamine
Female sexual dysfunction
Sex hormone
Journal
Revista internacional de andrologia
ISSN: 1698-0409
Titre abrégé: Rev Int Androl
Pays: Spain
ID NLM: 101500934
Informations de publication
Date de publication:
Mar 2024
Mar 2024
Historique:
received:
12
12
2022
accepted:
10
11
2023
medline:
13
5
2024
pubmed:
13
5
2024
entrez:
12
5
2024
Statut:
ppublish
Résumé
Dopamine and prolactin are the key mediators involved in sexual function in both males and females, but the role of dopamine in female sexual dysfunction (FSD) is still unclear. The aim was to investigate the possible role of dopamine and their relationship with sex steroid hormones (estrogen, progesterone and dehydroepiandrosterone; DHEA) and prolactin levels in Egyptian women suffering from sexual dysfunction. This study included 84 women having sexual dysfunction (FSD group) and 84 normal sexual function (control group). All women were subjected to the questionnaire to assess their demographic and gynecological data as well as female sexual function index (FSFI). Blood samples were collected from all women for measuring serum estradiol, progesterone, DHEA, prolactin and dopamine levels. FSD patients had significantly higher serum progesterone and DHEA and prolactin levels; while significantly lower dopamine and estradiol levels versus controls (
Identifiants
pubmed: 38735872
pii: S2333-0384(24)00001-1
doi: 10.22514/j.androl.2024.002
doi:
Substances chimiques
Dopamine
VTD58H1Z2X
Biomarkers
0
Prolactin
9002-62-4
Progesterone
4G7DS2Q64Y
Estradiol
4TI98Z838E
Dehydroepiandrosterone
459AG36T1B
Gonadal Steroid Hormones
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8-16Informations de copyright
©2024 The Author(s). Published by MRE Press.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.