Oncogene

Leukemia, Myeloid, Acute / genetics MDS1 and EVI1 Complex Locus Protein / metabolism Alcohol Oxidoreductases / metabolism Humans Animals DNA-Binding Proteins / metabolism Mice Co-Repressor Proteins / metabolism Protein Binding Cell Line, Tumor Cell Proliferation Cell Transformation, Neoplastic / genetics Transcription Factors / metabolism

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
17 May 2024
Historique:
medline: 15 5 2024
pubmed: 15 5 2024
entrez: 15 5 2024
Statut: ppublish

Résumé

Acute myeloid leukemia (AML) driven by the activation of

Identifiants

DOI: 10.1126/sciadv.adk9076 PMID: 38748792
pubmed: 38748792
doi: 10.1126/sciadv.adk9076
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadk9076

Auteurs

Dorien Pastoors (D)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Oncode Institute, Utrecht, Netherlands.
ORCID: 0000-0002-5322-1961

Marije Havermans (M)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Oncode Institute, Utrecht, Netherlands.
ORCID: 0009-0009-7996-9458

Roger Mulet-Lazaro (R)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Oncode Institute, Utrecht, Netherlands.
ORCID: 0000-0003-0298-7948

Duncan Brian (D)

Stem Cell Group, UCL Cancer Institute, University College London, London, UK.
ORCID: 0000-0002-3980-7341

Willy Noort (W)

Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Cancer Center Amsterdam, Cancer biology and immunology, Amsterdam, Netherlands.
ORCID: 0009-0007-0943-8729

Julius Grasel (J)

Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany.
Division of Experimental Hematology, German Cancer Research Center, DKFZ69120 Heidelberg, Germany.

Remco Hoogenboezem (R)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.

Leonie Smeenk (L)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Oncode Institute, Utrecht, Netherlands.
ORCID: 0000-0001-7025-8515

Jeroen A A Demmers (JAA)

Proteomics Center, Erasmus MC, Rotterdam, Netherlands.
ORCID: 0000-0002-8757-9611

Michael D Milsom (MD)

Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), 69120 Heidelberg, Germany.
Division of Experimental Hematology, German Cancer Research Center, DKFZ69120 Heidelberg, Germany.
ORCID: 0000-0002-3567-254X

Tariq Enver (T)

Stem Cell Group, UCL Cancer Institute, University College London, London, UK.

Richard W J Groen (RWJ)

Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Cancer Center Amsterdam, Cancer biology and immunology, Amsterdam, Netherlands.
ORCID: 0000-0002-5010-4604

Eric Bindels (E)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
ORCID: 0000-0001-9502-669X

Ruud Delwel (R)

Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands.
Oncode Institute, Utrecht, Netherlands.
ORCID: 0000-0001-6903-3271

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Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Leucémies › Leucémie myéloïde › Leucémie aigüe myéloïde › Oncogene
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéine du locus du complexe MDS1 et EVI1 › Oncogene
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › Oncogene
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Oncogene
questionsmedicales.fr › Eucaryotes › Animaux › Oncogene
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de liaison à l'ADN › Oncogene
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Oncogene
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Protéines de répression › Protéines corépressives › Oncogene
questionsmedicales.fr › Métabolisme › Liaison aux protéines › Oncogene
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale › Oncogene
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Oncogene
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › Transformation cellulaire néoplasique › Oncogene
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Oncogene