In Vivo and In Vitro Metabolic Fate and Urinary Detectability of Five Deschloroketamine Derivatives Studied by Means of Hyphenated Mass Spectrometry.

LC-HRMS/MS deschloro-N-cyclopropyl-ketamine deschloro-N-ethyl-ketamine deschloro-N-isopropyl-ketamine deschloro-N-propyl-ketamine deschloroketamine in vitro in vivo metabolism new psychoactive substance

Journal

Metabolites
ISSN: 2218-1989
Titre abrégé: Metabolites
Pays: Switzerland
ID NLM: 101578790

Informations de publication

Date de publication:
08 May 2024
Historique:
received: 11 04 2024
revised: 02 05 2024
accepted: 03 05 2024
medline: 24 5 2024
pubmed: 24 5 2024
entrez: 24 5 2024
Statut: epublish

Résumé

Ketamine derivatives such as deschloroketamine and deschloro-

Identifiants

pubmed: 38786747
pii: metabo14050270
doi: 10.3390/metabo14050270
pii:
doi:

Types de publication

Journal Article

Langues

eng

Auteurs

Fabian Frankenfeld (F)

Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, 66421 Homburg, Germany.

Lea Wagmann (L)

Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, 66421 Homburg, Germany.

Anush Abelian (A)

Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA 19104, USA.

Jason Wallach (J)

Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA 19104, USA.

Adeboye Adejare (A)

Department of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, PA 19104, USA.

Simon D Brandt (SD)

School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, UK.

Markus R Meyer (MR)

Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University, 66421 Homburg, Germany.

Classifications MeSH