Fatty Acids and Their Lipogenic Enzymes in Anorexia Nervosa Clinical Subtypes.
anorexia nervosa
desaturases
elongases
fatty acids
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
18 May 2024
18 May 2024
Historique:
received:
26
02
2024
revised:
11
05
2024
accepted:
15
05
2024
medline:
25
5
2024
pubmed:
25
5
2024
entrez:
25
5
2024
Statut:
epublish
Résumé
Disordered eating behavior differs between the restricting subtype (AN-R) and the binging and purging subtype (AN-BP) of anorexia nervosa (AN). Yet, little is known about how these differences impact fatty acid (FA) dysregulation in AN. To address this question, we analyzed 26 FAs and 7 FA lipogenic enzymes (4 desaturases and 3 elongases) in 96 women: 25 AN-R, 25 AN-BP, and 46 healthy control women. Our goal was to assess subtype-specific patterns. Lauric acid was significantly higher in AN-BP than in AN-R at the fasting timepoint (
Identifiants
pubmed: 38791555
pii: ijms25105516
doi: 10.3390/ijms25105516
pii:
doi:
Substances chimiques
Fatty Acids
0
Eicosapentaenoic Acid
AAN7QOV9EA
Lauric Acids
0
lauric acid
1160N9NU9U
Fatty Acid Elongases
EC 2.3.1.-
Fatty Acid Desaturases
EC 1.14.19.-
docosapentaenoic acid
NS3OZT14QT
Fatty Acids, Unsaturated
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIMH NIH HHS
ID : R01MH106781
Pays : United States