Determination of remifentanil in neonatal dried blood spots by liquid chromatography-tandem mass spectrometry.
Remifentanil
/ blood
Humans
Tandem Mass Spectrometry
/ methods
Infant, Newborn
Dried Blood Spot Testing
/ methods
Analgesics, Opioid
/ blood
Female
Fetal Blood
/ chemistry
Chromatography, Liquid
/ methods
Pregnancy
Piperidines
/ blood
Pilot Projects
Reproducibility of Results
Solid Phase Extraction
/ methods
dried blood spots
labour
patient-controlled analgesia
remifentanil
umbilical cord blood
Journal
Acta pharmaceutica (Zagreb, Croatia)
ISSN: 1846-9558
Titre abrégé: Acta Pharm
Pays: Poland
ID NLM: 9303678
Informations de publication
Date de publication:
01 Jun 2024
01 Jun 2024
Historique:
accepted:
28
03
2024
medline:
30
5
2024
pubmed:
30
5
2024
entrez:
30
5
2024
Statut:
epublish
Résumé
Remifentanil is an ultra-short-acting synthetic opioid-class analgesic which might be increasingly used "off-label" as pain management during labour. Side effects in parturients during labour, and in the infant at birth are of particular concern, especially respiratory depression which is concentration-dependent, and can occur at levels as low as 3-5 ng mL
Identifiants
pubmed: 38815198
pii: acph-2024-0010
doi: 10.2478/acph-2024-0010
doi:
Substances chimiques
Remifentanil
P10582JYYK
Analgesics, Opioid
0
Piperidines
0
Types de publication
Journal Article
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
343-354Informations de copyright
© 2024 Jurij Trontelj et al., published by Sciendo.
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