Robotic partial nephrectomy is associated with a significantly decreased rate of postoperative pseudoaneurysm compared to open and laparoscopic partial nephrectomy.


Journal

Journal of robotic surgery
ISSN: 1863-2491
Titre abrégé: J Robot Surg
Pays: England
ID NLM: 101300401

Informations de publication

Date de publication:
04 Jun 2024
Historique:
received: 14 04 2024
accepted: 27 05 2024
medline: 4 6 2024
pubmed: 4 6 2024
entrez: 4 6 2024
Statut: epublish

Résumé

While partial nephrectomy offers oncologic efficacy and preserves renal function for T1 renal tumors, renal artery pseudoaneurysm (RAP) remains a rare but potentially life-threatening complication. This study compared RAP incidence across robotic-assisted (RAPN), laparoscopic (LPN), and open (OPN) partial nephrectomies in a large tertiary oncological center. This retrospective study analyzed 785 patients undergoing partial nephrectomy between 2012 and 2022 (398 RAPN, 122 LPN, 265 OPN). Data included demographics, tumor size/location, surgical type, clinical presentation, treatment, and post-operative outcomes. The primary outcome was RAP incidence, with secondary outcomes including presentation, treatment efficacy, and renal function. Seventeen patients (2.1%) developed RAP, presenting with massive hematuria (100%), hemorrhagic shock (5.8%), and clot retention (23%). The median onset was 12 days postoperatively. RAP occurred in 4 (1%), 4 (3.3%), and 9 (3.4%) patients following RAPN, LPN, and OPN, respectively (p = 0.04). Only operative length and surgical approach were independently associated with RAP. Selective embolization achieved immediate bleeding control in 94%, with one patient requiring a second embolization. No additional surgery or nephrectomy was needed. Estimated GFR at one year was similar across both groups (p = 0.53). RAPN demonstrated a significantly lower RAP incidence compared to LPN and OPN (p = 0.04). Emergency angiographic embolization proved effective, with no long-term renal function impact. This retrospective study lacked randomization and long-term follow-up. Further research with larger datasets and longer follow-ups is warranted. This study suggests that robotic-assisted partial nephrectomy is associated with a significantly lower risk of RAP compared to traditional approaches. Emergency embolization effectively treats RAP without compromising long-term renal function.

Identifiants

pubmed: 38833079
doi: 10.1007/s11701-024-01999-3
pii: 10.1007/s11701-024-01999-3
doi:

Types de publication

Journal Article Comparative Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

241

Informations de copyright

© 2024. The Author(s).

Références

Mir MC, Derweesh I, Porpiglia F (2017) Partial nephrectomy versus radical nephrectomy for clinical T1b and T2 renal tumors: a systematic review and meta-analysis of comparative studies. Eur Urol 71(4):606–617
doi: 10.1016/j.eururo.2016.08.060 pubmed: 27614693
Kobayashi S, Mutaguchi J, Kashiwagi E (2021) Clinical advantages of robot-assisted partial nephrectomy versus laparoscopic partial nephrectomy in terms of global and split renal functions: a propensity score-matched comparative analysis. Int J Urol 28:630–636
doi: 10.1111/iju.14525 pubmed: 33660374
Bray G, Bahadori A, Mao D (2022) Benefits of robotic assisted vs. traditional laparoscopic partial nephrectomy: a single surgeon comparative study. J Clin Med 11:6974
doi: 10.3390/jcm11236974 pubmed: 36498549 pmcid: 9741158
Williams SB, Kacker R, Alemozaffar M (2013) Robotic partial nephrectomy versus laparoscopic partial nephrectomy: a single laparoscopic trained surgeon’s experience in the development of a robotic partial nephrectomy program. World J Urol 31:793–798
doi: 10.1007/s00345-011-0648-5 pubmed: 21274541
Guglielmetti GB, dos Anjos GC, Sawczyn G et al (2022) A prospective, randomized trial comparing the outcomes of open vs laparoscopic partial nephrectomy. J Urol 208:259–267
doi: 10.1097/JU.0000000000002695 pubmed: 35404109
Kutikov A, Uzzo RG (2009) The R.E.N.A.L. nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth. J Urol 182(3):844–853
doi: 10.1016/j.juro.2009.05.035 pubmed: 19616235
Hyams ES, Pierorazio P, Proteek O (2011) Iatrogenic vascular lesions after minimally invasive partial nephrectomy: a multi-institutional study of clinical and renal functional outcomes. Urology 78(4):820–826
doi: 10.1016/j.urology.2011.04.063 pubmed: 21813164
Lu Q, Zhao X, Zhang S (2023) Robot-assisted simple enucleation versus standard robot-assisted partial nephrectomy for low- or intermediate-complexity, clinical T1 renal tumors: a randomized controlled noninferiority trial. Euro Urol Oncol 17:S2588-9311
Gershman B, Thompson RH, Boorjian SA (2018) Radical versus partial nephrectomy for cT1 renal cell carcinoma. Eur Urol 74(6):825–832
doi: 10.1016/j.eururo.2018.08.028 pubmed: 30262341
Heuer R, Gill IS, Guazzoni G (2009) A critical analysis of the actual role of minimally invasive surgery and active surveillance for kidney cancer. Eur Urol 57(2):223–232
doi: 10.1016/j.eururo.2009.10.023 pubmed: 19853989
Ghoneim TP, Thornton RH, Solomon SB et al (2011) Selective arterimbolization for pseudoaneurysms and arteriovenous fistula of renal artery branches following partial nephrectomy. J Urol 185:2061–2065
doi: 10.1016/j.juro.2011.02.049 pubmed: 21496835
Chavali JSS, Bertolo R, Kara O (2018) Renal arterial pseudoaneurysm after partial nephrectomy: literature review and single-center analysis of predictive factors and renal functional outcomes. J Laparoendosc Adv Surg Tech 29(1):45–50
doi: 10.1089/lap.2018.0364
Saoud R, Heidar NA, Aizen J (2021) Long-term renal function following selective angioembolization for iatrogenic vascular lesions after partial nephrectomy: a matched case-control study. Clin Urol 62:267–273
Jain S, Nyirenda T, Yates J (2013) Incidence of renal artery pseudoaneurysm following open and minimally invasive partial nephrectomy: a systematic review and comparative analysis. J Urol 189:1643–2164
doi: 10.1016/j.juro.2012.11.170 pubmed: 23219544
Leow JJ, Heah NH, Chang SL (2016) Outcomes after robotic versus laparoscopic partial nephrectomy: an updated meta-analysis of 4919 patients. J Urol 196(5):1371–1377
doi: 10.1016/j.juro.2016.06.011 pubmed: 27291654
Verges DP, Margules A, Weprin S (2017) Delayed renal artery pseudoaneurysm after robotic partial nephrectomy. J Robotic Surg 11:275–277
doi: 10.1007/s11701-017-0676-2
Strobl FF, D’Anastasi M, Hinzpeter R (2016) Renal pseudoaneurysms and arteriovenous fistulas as a complication of nephron-sparing partial nephrectomy: technical and functional outcomes of patients treated with selective microcoil embolization during a ten-year period. Interv Radiol 188:188–194
Guo H, Wang C, Yang M (2017) Management of iatrogenic renal arteriovenous fistula and renal arterial pseudoaneurysm by transarterial embolization: a single center analysis and outcomes. Medicine 96(40):E8187
doi: 10.1097/MD.0000000000008187 pubmed: 28984770 pmcid: 5738006
Shapiro EY, Hakimi AA, Hyams ES (2009) Laparoscopy and robotics renal artery pseudoaneurysm following laparoscopic partial nephrectomy. Urology 74:819–823
doi: 10.1016/j.urology.2009.03.056 pubmed: 19647302
Nadu A, Kleinmann N, Laufer M, Dotan Z, Winkler H (2009) Laparoscopic partial nephrectomy for central tumors: analysis of perioperative outcomes and complications. J Urol 181:42–47
doi: 10.1016/j.juro.2008.09.014 pubmed: 19012908

Auteurs

Husny Mahmud (H)

Department of Urology, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel. Husny.mahmud@sheba.health.gov.il.

Boris Haitovic (B)

Unit of Interventional Radiology, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Dorit E Zilberman (DE)

Department of Urology, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Barak Rosenzweig (B)

Department of Urology, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Menachem Laufer (M)

Department of Urology, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Orith Portnoy (O)

Diagnostic Imaging Department, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Eddie Fridman (E)

Pathology Department, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Zohar A Dotan (ZA)

Department of Urology, Affiliated to the Faculty of Medicine, Sheba Medical Center, Tel Aviv University, Tel Hashomer, Tel Aviv, Israel.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH