Two-stage evolution of mammalian adipose tissue thermogenesis.

Thermogenesis / genetics Animals Uncoupling Protein 1 / genetics Adipose Tissue, Brown / metabolism Marsupialia / genetics Biological Evolution Eutheria / genetics Transcriptome Evolution, Molecular Phylogeny Adipose Tissue, Beige / metabolism Humans

Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
07 Jun 2024
Historique:
medline: 6 6 2024
pubmed: 6 6 2024
entrez: 6 6 2024
Statut: ppublish

Résumé

Brown adipose tissue (BAT) is a heater organ that expresses thermogenic uncoupling protein 1 (UCP1) to maintain high body temperatures during cold stress. BAT thermogenesis is considered an overarching mammalian trait, but its evolutionary origin is unknown. We show that adipose tissue of marsupials, which diverged from eutherian mammals

Identifiants

DOI: 10.1126/science.adg1947 PMID: 38843333
pubmed: 38843333
doi: 10.1126/science.adg1947
doi:

Substances chimiques

Uncoupling Protein 1 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1111-1117

Commentaires et corrections

Type : CommentIn

Auteurs

Susanne Keipert (S)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.
ORCID: 0000-0002-6618-7379

Michael J Gaudry (MJ)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.
ORCID: 0000-0001-8411-0415

Maria Kutschke (M)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.

Michaela Keuper (M)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.
ORCID: 0000-0003-0319-3509

Margeoux A S Dela Rosa (MAS)

Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.
ORCID: 0000-0002-9586-763X

Yiming Cheng (Y)

Institute of Neuronal Cell Biology, Technical University of Munich, 80802 Munich, Germany.
Munich Cluster of Systems Neurology, 81377 Munich, Germany.
Institute for Diabetes and Obesity (IDO), Helmholtz Zentrum München, 85764 Munich, Germany.
ORCID: 0009-0006-4270-7292

José M Monroy Kuhn (JM)

Computational Discovery Research, Institute for Diabetes and Obesity (IDO), Helmholtz Diabetes Center (HDC), Helmholtz Zentrum Munich, German Research Center for Environmental Health, German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
ORCID: 0000-0002-4748-8854

Rutger Laterveer (R)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.
ORCID: 0000-0003-2016-665X

Camila A Cotrim (CA)

Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.
ORCID: 0000-0002-9176-5767

Peter Giere (P)

Museum für Naturkunde-Leibniz Institute for Evolution and Biodiversity Science, 10115 Berlin, Germany.
ORCID: 0000-0002-5570-0085

Fabiana Perocchi (F)

Institute of Neuronal Cell Biology, Technical University of Munich, 80802 Munich, Germany.
Munich Cluster of Systems Neurology, 81377 Munich, Germany.
Institute for Diabetes and Obesity (IDO), Helmholtz Zentrum München, 85764 Munich, Germany.

Regina Feederle (R)

Monoclonal Antibody Core Facility, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764 Neuherberg, Germany.
ORCID: 0000-0002-3981-367X

Paul G Crichton (PG)

Biomedical Research Centre, Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK.
ORCID: 0000-0003-3786-8359

Dominik Lutter (D)

Computational Discovery Research, Institute for Diabetes and Obesity (IDO), Helmholtz Diabetes Center (HDC), Helmholtz Zentrum Munich, German Research Center for Environmental Health, German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
ORCID: 0000-0002-8800-0683

Martin Jastroch (M)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-106 91 Stockholm, Sweden.
ORCID: 0000-0003-0358-3865

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Classifications MeSH

questionsmedicales.fr › Phénomènes biologiques › Adaptation biologique › Adaptation physiologique › Régulation de la température corporelle › Thermogenèse › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Eucaryotes › Animaux › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines mitochondriales › Protéines de transport de la membrane mitochondriale › Protéines de découplage mitochondrial › Protéine-1 de découplage › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Tissu adipeux brun › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Marsupialia › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Phénomènes biologiques › Évolution biologique › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Transcriptome › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Phénomènes biologiques › Évolution biologique › Évolution moléculaire › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Sciences de l'information › Phylogenèse › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Tissus › Tissu conjonctif › Tissu adipeux › Tissu adipeux beige › Two-stage evolution of mammalian adipose...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Two-stage evolution of mammalian adipose...