Indocyanine green near-infrared fluorescence-assisted video endoscopic inguinal lymph node dissection for rectal cancer: a single-center experience.
Humans
Indocyanine Green
Rectal Neoplasms
/ surgery
Male
Lymph Node Excision
/ methods
Female
Middle Aged
Retrospective Studies
Aged
Feasibility Studies
Video-Assisted Surgery
/ methods
Operative Time
Lymphatic Metastasis
Inguinal Canal
/ surgery
Postoperative Complications
/ etiology
Adult
Lymph Nodes
/ pathology
Coloring Agents
Fluorescence
Fluorescence imaging
Indocyanine green
Rectal cancer
Video endoscopic inguinal lymph node dissection
Journal
Techniques in coloproctology
ISSN: 1128-045X
Titre abrégé: Tech Coloproctol
Pays: Italy
ID NLM: 9613614
Informations de publication
Date de publication:
06 Jun 2024
06 Jun 2024
Historique:
received:
11
12
2023
accepted:
15
05
2024
medline:
7
6
2024
pubmed:
7
6
2024
entrez:
6
6
2024
Statut:
epublish
Résumé
This study aimed to investigate the safety and feasibility of indocyanine green near-infrared fluorescence (ICG-NIR) fluorescence-guided video-endoscopic inguinal lymphadenectomy (VEIL) for rectal cancer with inguinal lymph node metastasis (ILNM). A retrospective analysis was conducted on 11 patients with rectal cancer who underwent ICG-NIR fluorescence-guided VEIL, assessing various parameters such as operation time, intraoperative bleeding, number of harvested lymph nodes, intraoperative and postoperative complications, and follow-up. Regarding surgical procedures for ILNM, unilateral surgery was performed in 7 cases (54.5%) and bilateral surgery in 4 cases (45.5%). Among these 15 ICG-NIR-guided VEIL surgeries in 11 patients, positive fluorescence visualization was achieved in 13 operations (86.7%). The median estimated blood loss was 10 ml, and the median operation time was 90 min. One case (6.7%) required conversion to open surgery. The median duration of the drain tube was 12 days, and the median length of postoperative hospital stay was 20 days. Postoperative complications were observed, including incisional infection in 2 cases (18.2%), lymphatic leakage in 5 cases (45.5%), urinary infection in 1 case (9.1%), and pneumonia in 3 cases (27.3%). Complications such as skin necrosis, lower limb venous thrombosis, lower limb swelling, or impaired movement were observed during the postoperative follow-up period. No cases of primary lesion, groin, or pelvic lymph node recurrence were observed. ICG-NIR fluorescence-guided VEIL is a safe and feasible surgical treatment for rectal cancer with ILNM. ICG fluorescence guidance holds promise as a more personalized and precise approach for VEIL in rectal cancer surgery.
Sections du résumé
BACKGROUND
BACKGROUND
This study aimed to investigate the safety and feasibility of indocyanine green near-infrared fluorescence (ICG-NIR) fluorescence-guided video-endoscopic inguinal lymphadenectomy (VEIL) for rectal cancer with inguinal lymph node metastasis (ILNM).
METHODS
METHODS
A retrospective analysis was conducted on 11 patients with rectal cancer who underwent ICG-NIR fluorescence-guided VEIL, assessing various parameters such as operation time, intraoperative bleeding, number of harvested lymph nodes, intraoperative and postoperative complications, and follow-up.
RESULTS
RESULTS
Regarding surgical procedures for ILNM, unilateral surgery was performed in 7 cases (54.5%) and bilateral surgery in 4 cases (45.5%). Among these 15 ICG-NIR-guided VEIL surgeries in 11 patients, positive fluorescence visualization was achieved in 13 operations (86.7%). The median estimated blood loss was 10 ml, and the median operation time was 90 min. One case (6.7%) required conversion to open surgery. The median duration of the drain tube was 12 days, and the median length of postoperative hospital stay was 20 days. Postoperative complications were observed, including incisional infection in 2 cases (18.2%), lymphatic leakage in 5 cases (45.5%), urinary infection in 1 case (9.1%), and pneumonia in 3 cases (27.3%). Complications such as skin necrosis, lower limb venous thrombosis, lower limb swelling, or impaired movement were observed during the postoperative follow-up period. No cases of primary lesion, groin, or pelvic lymph node recurrence were observed.
CONCLUSION
CONCLUSIONS
ICG-NIR fluorescence-guided VEIL is a safe and feasible surgical treatment for rectal cancer with ILNM. ICG fluorescence guidance holds promise as a more personalized and precise approach for VEIL in rectal cancer surgery.
Identifiants
pubmed: 38844577
doi: 10.1007/s10151-024-02937-z
pii: 10.1007/s10151-024-02937-z
doi:
Substances chimiques
Indocyanine Green
IX6J1063HV
Coloring Agents
0
Types de publication
Journal Article
Evaluation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
64Subventions
Organisme : Young and Middle-aged Backbone Training Project in the Health System of Fujian Province
ID : 2019-ZQN-45
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Construction Project of Fujian Province Minimally Invasive Medical Center
ID : [2017]171
Organisme : Natural Science Foundation of Fujian Province
ID : 2020J011030
Organisme : Natural Science Foundation of Fujian Province
ID : 2020J011030
Organisme : Medical Science Research Foundation of Beijing Medical and Health Foundation
ID : B20062DS
Organisme : Fujian provincial health technology project
ID : 2020CXA025
Organisme : Bethune Charitable Foundation
ID : X-J-2018-004
Informations de copyright
© 2024. Springer Nature Switzerland AG.
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