Effect of the COVID-19 pandemic on Vogt-Koyanagi-Harada disease.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
08 Jun 2024
Historique:
received: 24 02 2024
accepted: 04 06 2024
medline: 9 6 2024
pubmed: 9 6 2024
entrez: 8 6 2024
Statut: epublish

Résumé

To determine the disease prevalence rate and clinical characteristics of Vogt-Koyanagi-Harada (VKH) disease among new patients before and after the declaration of a state of emergency (April 7, 2020) in Japan. New patients and patients with newly diagnosed VKH disease were categorized into "Before" and "After" groups based on the initial visit. The prevalence rate, sex ratio, and age of patients newly diagnosed with VKH were compared between the groups. Best-corrected visual acuity (BCVA) and recurrence rates were compared among 59 patients observed for > 12 months after receiving pulse steroid therapy. For reference, we also examined the prevalence rate of patients newly diagnosed with acute angle closure (AAC) in the Before and After groups. The prevalence rates of VKH disease among newly diagnosed patients (P < 0.05) or patients with AAC (P < 0.001) were significantly higher in the After group. No significant differences in sex ratio or age of VKH disease were observed in both groups. BCVA and recurrence rates showed no significant differences. The COVID-19 pandemic increased the prevalence of VKH disease among new patients compared with that of AAC. However, the clinical features of VKH disease were unlikely affected by the COVID-19 pandemic.

Identifiants

pubmed: 38851824
doi: 10.1038/s41598-024-63957-1
pii: 10.1038/s41598-024-63957-1
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

13211

Informations de copyright

© 2024. The Author(s).

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Auteurs

Tetsuya Muto (T)

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan. ueda.castle@gmail.com.
Department of Ophthalmology, Imaizumi Eye Hospital, 20-9 Domaecho, Koriyama, 963-8877, Japan. ueda.castle@gmail.com.
Department of Ophthalmology, Fukushima Medical University, Fukushima, 960-1295, Japan. ueda.castle@gmail.com.

Masaaki Sakamoto (M)

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan.

Shoichiro Kusuda (S)

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan.

Yasuo Haruyama (Y)

Dokkyo Medical University Center for Research Cooperative and Support, Mibu, 321-0293, Japan.

Shigeki Machida (S)

Department of Ophthalmology, Dokkyo Medical University Saitama Medical Center, Koshigaya, 343-8555, Japan.

Shinichiro Imaizumi (S)

Department of Ophthalmology, Imaizumi Eye Hospital, 20-9 Domaecho, Koriyama, 963-8877, Japan.

Tetsuju Sekiryu (T)

Department of Ophthalmology, Fukushima Medical University, Fukushima, 960-1295, Japan.

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