Advanced optical assessment and modeling of extrusion bioprinting.
Biofabrication
Bioink
Bioprinting
Extrusion
Modeling
Rheology
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
17 06 2024
17 06 2024
Historique:
received:
20
02
2024
accepted:
03
06
2024
medline:
18
6
2024
pubmed:
18
6
2024
entrez:
17
6
2024
Statut:
epublish
Résumé
In the context of tissue engineering, biofabrication techniques are employed to process cells in hydrogel-based matrices, known as bioinks, into complex 3D structures. The aim is the production of functional tissue models or even entire organs. The regenerative production of biological tissues adheres to a multitude of criteria that ultimately determine the maturation of a functional tissue. These criteria are of biological nature, such as the biomimetic spatial positioning of different cell types within a physiologically and mechanically suitable matrix, which enables tissue maturation. Furthermore, the processing, a combination of technical procedures and biological materials, has proven highly challenging since cells are sensitive to stress, for example from shear and tensile forces, which may affect their vitality. On the other hand, high resolutions are pursued to create optimal conditions for subsequent tissue maturation. From an analytical perspective, it is prudent to first investigate the printing behavior of bioinks before undertaking complex biological tests. According to our findings, conventional shear rheological tests are insufficient to fully characterize the printing behavior of a bioink. For this reason, we have developed optical methods that, complementarily to the already developed tests, allow for quantification of printing quality and further viscoelastic modeling of bioinks.
Identifiants
pubmed: 38886452
doi: 10.1038/s41598-024-64039-y
pii: 10.1038/s41598-024-64039-y
doi:
Substances chimiques
Hydrogels
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
13972Subventions
Organisme : Deutsche Forschungsgemeinschaft (German Research Foundation)
ID : 326998133
Informations de copyright
© 2024. The Author(s).
Références
Biofabrication. 2016 Sep 16;8(3):035020
pubmed: 27634915
Biomater Sci. 2022 Sep 13;10(18):5054-5080
pubmed: 35876134
APL Bioeng. 2021 Feb 04;5(1):011502
pubmed: 33564740
Biomater Sci. 2018 May 1;6(5):915-946
pubmed: 29492503
Int J Mol Sci. 2022 Apr 26;23(9):
pubmed: 35563143
Biofabrication. 2017 Nov 30;10(1):014102
pubmed: 28976364
Int J Pharm. 2022 Mar 5;615:121506
pubmed: 35085727
Biofabrication. 2021 Jun 07;13(3):
pubmed: 34020427
Front Bioeng Biotechnol. 2023 Mar 20;11:1147943
pubmed: 37020512
Biomater Sci. 2021 Feb 7;9(3):535-573
pubmed: 33185203
Mol Reprod Dev. 2015 Jul-Aug;82(7-8):518-29
pubmed: 26153368
Biofabrication. 2016 Oct 07;8(4):045004
pubmed: 27716633
Trends Biotechnol. 2018 Apr;36(4):384-402
pubmed: 29137814
Chem Rev. 2020 Oct 14;120(19):11028-11055
pubmed: 32856892
Sci Rep. 2023 Jul 12;13(1):11253
pubmed: 37438423
Biofabrication. 2023 Oct 11;16(1):
pubmed: 37769669
Tissue Eng Part A. 2021 Sep;27(17-18):1168-1181
pubmed: 33218292
Biofabrication. 2021 Apr 08;13(3):
pubmed: 33601340
Biofabrication. 2015 Nov 02;7(4):045002
pubmed: 26523399
J Pharm Anal. 2021 Oct;11(5):564-579
pubmed: 34765269
J Mol Recognit. 2018 Sep;31(9):e2719
pubmed: 29701269
Biofabrication. 2019 Aug 22;11(4):045016
pubmed: 31342915
Polymers (Basel). 2022 Aug 21;14(16):
pubmed: 36015671
Materials (Basel). 2018 Mar 20;11(3):
pubmed: 29558424
Nat Protoc. 2016 Apr;11(4):727-46
pubmed: 26985572
J Biomed Mater Res B Appl Biomater. 2021 Aug;109(8):1090-1104
pubmed: 33277973
Biofabrication. 2018 Jun 18;10(3):034105
pubmed: 29809162
Int J Pept Res Ther. 2014;20:77-85
pubmed: 24489527
MedComm (2020). 2022 Dec 24;4(1):e194
pubmed: 36582305
Biofabrication. 2023 Apr 04;15(3):
pubmed: 36927673
Biofabrication. 2022 Jan 24;14(2):
pubmed: 34875631
Macromol Biosci. 2022 Feb;22(2):e2100331
pubmed: 34779129