Structural Features Influencing the Bioactive Conformation of Angiotensin II and Angiotensin A: Relationship between Receptor Desensitization, Addiction, and the Blood-Brain Barrier.

Blood-Brain Barrier / metabolism Angiotensin II / metabolism Humans Animals Receptor, Angiotensin, Type 1 / metabolism Protein Conformation
G-protein coupled receptor addiction angiotensin II arginine bisartan blood–brain barrier conformation of angiotensin coronavirus disease 2019 receptor desensitization

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
26 May 2024
Historique:
received: 27 03 2024
revised: 04 05 2024
accepted: 08 05 2024
medline: 19 6 2024
pubmed: 19 6 2024
entrez: 19 6 2024
Statut: epublish

Résumé

The N-terminal portion of the octapeptide angiotensin II (DRVYIHPF; AngII), a vasopressor peptide that favorably binds to, and activates, AngII type 1 receptor (AT

Identifiants

DOI: 10.3390/ijms25115779 PMID: 38891966
pubmed: 38891966
pii: ijms25115779
doi: 10.3390/ijms25115779
pii:
doi:

Substances chimiques

Angiotensin II 11128-99-7
Receptor, Angiotensin, Type 1 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Graham J Moore (GJ)

Pepmetics Inc., 772 Murphy Place, Victoria, BC V8Y 3H4, Canada.
Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.

Harry Ridway (H)

Institute for Sustainable Industries and Liveable Cities, Victoria University, Melbourne, VIC 8001, Australia.

Laura Kate Gadanec (LK)

Institute for Health and Sport, Immunology and Translational Research, Victoria University, Melbourne, VIC 3030, Australia.
ORCID: 0000-0002-4801-8061

Vasso Apostolopoulos (V)

Institute for Health and Sport, Immunology and Translational Research, Victoria University, Melbourne, VIC 3030, Australia.
Immunology Program, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne, VIC 3021, Australia.
ORCID: 0000-0001-6788-2771

Anthony Zulli (A)

Institute for Health and Sport, Immunology and Translational Research, Victoria University, Melbourne, VIC 3030, Australia.

Jordan Swiderski (J)

Institute for Health and Sport, Immunology and Translational Research, Victoria University, Melbourne, VIC 3030, Australia.
ORCID: 0000-0002-3613-2406

Konstantinos Kelaidonis (K)

NewDrug/NeoFar PC, Patras Science Park, 26504 Patras, Greece.

Veroniki P Vidali (VP)

Institute of Nanoscience and Nanotechnology, National Centre for Scientific Research "Demokritos", 15341 Athens, Greece.
ORCID: 0000-0001-9020-8726

Minos-Timotheos Matsoukas (MT)

Department of Biomedical Engineering, University of West Attica, 12243 Athens, Greece.

Christos T Chasapis (CT)

Institute of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece.
ORCID: 0000-0002-8728-6245

John M Matsoukas (JM)

Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 1N4, Canada.
Institute for Health and Sport, Immunology and Translational Research, Victoria University, Melbourne, VIC 3030, Australia.
NewDrug/NeoFar PC, Patras Science Park, 26504 Patras, Greece.
Department of Chemistry, University of Patras, 26504 Patras, Greece.
ORCID: 0000-0001-5554-2964

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Classifications MeSH

questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Barrière hémato-encéphalique › Structural Features Influencing the Bioactive...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Angiotensines › Angiotensine-II › Structural Features Influencing the Bioactive...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Structural Features Influencing the Bioactive...
questionsmedicales.fr › Eucaryotes › Animaux › Structural Features Influencing the Bioactive...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteurs aux angiotensines › Récepteur de type 1 à l'angiotensine-II › Structural Features Influencing the Bioactive...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structural Features Influencing the Bioactive...