Optimizing Antimicrobial Peptide Design: Integration of Cell-Penetrating Peptides, Amyloidogenic Fragments, and Amino Acid Residue Modifications.

Cell-Penetrating Peptides / chemistry Antimicrobial Peptides / pharmacology Microbial Sensitivity Tests Anti-Bacterial Agents / pharmacology Amino Acids / chemistry Drug Design Amyloidogenic Proteins / chemistry
Antp fragment TAT fragment amyloidogenic regions antimicrobial peptides cell-penetrating peptide ribosomal S1 protein

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 May 2024
Historique:
received: 27 04 2024
revised: 27 05 2024
accepted: 29 05 2024
medline: 19 6 2024
pubmed: 19 6 2024
entrez: 19 6 2024
Statut: epublish

Résumé

The escalating threat of multidrug-resistant pathogens necessitates innovative approaches to combat infectious diseases. In this study, we examined peptides R23F

Identifiants

DOI: 10.3390/ijms25116030 PMID: 38892216
pubmed: 38892216
pii: ijms25116030
doi: 10.3390/ijms25116030
pii:
doi:

Substances chimiques

Cell-Penetrating Peptides 0
Antimicrobial Peptides 0
Anti-Bacterial Agents 0
Amino Acids 0
Amyloidogenic Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Sergey V Kravchenko (SV)

Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.
ORCID: 0000-0002-1261-7919

Pavel A Domnin (PA)

Biology Faculty, Lomonosov Moscow State University, 119991 Moscow, Russia.
Gamaleya Research Centre of Epidemiology and Microbiology, 123098 Moscow, Russia.
ORCID: 0000-0002-4130-1753

Sergei Y Grishin (SY)

Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.
ORCID: 0000-0001-7373-9808

Alena P Zakhareva (AP)

Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.

Anastasiia A Zakharova (AA)

Institute of Cytology of the Russian Academy of Sciences, Tikhoretsky Ave. 4, 194064 St. Petersburg, Russia.

Leila G Mustaeva (LG)

The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.

Elena Y Gorbunova (EY)

The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.

Margarita I Kobyakova (MI)

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.
Research Institute of Clinical and Experimental Lymphology-Branch of the Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, 630060 Novosibirsk, Russia.
ORCID: 0000-0002-6846-9994

Alexey K Surin (AK)

Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.
The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
State Research Center for Applied Microbiology and Biotechnology, 142279 Obolensk, Russia.
ORCID: 0000-0001-9246-7369

Darya V Poshvina (DV)

Institute of Environmental and Agricultural Biology (X-BIO), Tyumen State University, 625003 Tyumen, Russia.

Roman S Fadeev (RS)

Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.

Viacheslav N Azev (VN)

The Branch of the Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
ORCID: 0000-0003-3275-4811

Olga S Ostroumova (OS)

Institute of Cytology of the Russian Academy of Sciences, Tikhoretsky Ave. 4, 194064 St. Petersburg, Russia.

Svetlana A Ermolaeva (SA)

Gamaleya Research Centre of Epidemiology and Microbiology, 123098 Moscow, Russia.
ORCID: 0000-0003-3396-6816

Oxana V Galzitskaya (OV)

Gamaleya Research Centre of Epidemiology and Microbiology, 123098 Moscow, Russia.
Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Russia.
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, 142290 Pushchino, Russia.
ORCID: 0000-0002-3962-1520

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides de pénétration cellulaire › Optimizing Antimicrobial Peptide Design:...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides antimicrobiens › Optimizing Antimicrobial Peptide Design:...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Optimizing Antimicrobial Peptide Design:...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Optimizing Antimicrobial Peptide Design:...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Optimizing Antimicrobial Peptide Design:...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › Découverte de médicament › Conception de médicament › Optimizing Antimicrobial Peptide Design:...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Amyloïde › Protéines amyloïdogènes › Optimizing Antimicrobial Peptide Design:...