Neuroblastoma / genetics Animals Humans Mice Genes, Tumor Suppressor Gene Expression Regulation, Neoplastic Zebrafish / genetics Cell Line, Tumor Cell Lineage / genetics Neural Crest / metabolism Schwann Cells / metabolism

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
21 Jun 2024
Historique:
medline: 21 6 2024
pubmed: 21 6 2024
entrez: 21 6 2024
Statut: ppublish

Résumé

Neuroblastoma is a childhood developmental cancer; however, its embryonic origins remain poorly understood. Moreover, in-depth studies of early tumor-driving events are limited because of the lack of appropriate models. Herein, we analyzed RNA sequencing data obtained from human neuroblastoma samples and found that loss of expression of trunk neural crest-enriched gene

Identifiants

DOI: 10.1126/sciadv.ado1583 PMID: 38905335
pubmed: 38905335
doi: 10.1126/sciadv.ado1583
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eado1583

Auteurs

Elina Fredlund (E)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0009-0006-1986-1267

Stina Andersson (S)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0000-0003-3226-4740

Elien Hilgert (E)

Center for Medical Genetics, Ghent University, Ghent, Belgium.
ORCID: 0000-0002-4715-6972

Ezequiel Monferrer (E)

Department of Pathology, Medical School, University of Valencia-INCLIVA Biomedical Health Research Institute, Valencia, Spain.
Low Prevalence Tumors, Centro de Investigación Biomédica En Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain.

Guadalupe Álvarez-Hernán (G)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0000-0001-5725-6515

Sinan Karakaya (S)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.

Siebe Loontiens (S)

Center for Medical Genetics, Ghent University, Ghent, Belgium.
ORCID: 0000-0002-4602-4580

Jan Willem Bek (JW)

Center for Medical Genetics, Ghent University, Ghent, Belgium.
ORCID: 0000-0003-1337-1970

Tomas Gregor (T)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0000-0002-7974-1316

Estelle Lecomte (E)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.

Emma Magnusson (E)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.

Enrika Miltenyte (E)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.

Marie Cabirol (M)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.

Michail Kyknas (M)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0009-0004-0813-2670

Niklas Engström (N)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0000-0003-2399-985X

Marie Arsenian Henriksson (MA)

Department of Microbiology, Tumor and Cell Biology (MTC), Biomedicum B7, Karolinska Institute, Stockholm, Sweden.
Department of Laboratory Medicine, Lund University, Lund, Sweden.
ORCID: 0000-0001-6376-7792

Emma Hammarlund (E)

Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
Department of Laboratory Medicine, Lund University, Lund, Sweden.
ORCID: 0000-0001-7625-4793

Jared S Rosenblum (JS)

Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Development, National Institutes of Health, Bethesda, MD 20892, USA.
ORCID: 0000-0001-5941-9082

Rosa Noguera (R)

Department of Pathology, Medical School, University of Valencia-INCLIVA Biomedical Health Research Institute, Valencia, Spain.
Low Prevalence Tumors, Centro de Investigación Biomédica En Red de Cáncer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain.
ORCID: 0000-0003-4546-7459

Frank Speleman (F)

Center for Medical Genetics, Ghent University, Ghent, Belgium.

Johan van Nes (J)

Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

Sofie Mohlin (S)

Division of Pediatrics, Department of Clinical Sciences, Lund University, Lund, Sweden.
Lund University Cancer Center, Lund University, Lund, Sweden.
Lund Stem Cell Center, Lund University, Lund, Sweden.
ORCID: 0000-0002-2458-3963

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Tumeurs neuroectodermiques primitives › Tumeurs neuroectodermiques primitives périphériques › Neuroblastome ›
questionsmedicales.fr › Eucaryotes › Animaux ›
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains ›
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris ›
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Gènes › Gènes suppresseurs de tumeur ›
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes tumoraux ›
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré ›
questionsmedicales.fr › Cellules › Cellules cultivées › Cellules cancéreuses en culture › Lignée cellulaire tumorale ›
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Développement embryonnaire et foetal › Développement embryonnaire › Lignage cellulaire ›
questionsmedicales.fr › Structures de l'embryon › Crête neurale ›
questionsmedicales.fr › Cellules › Névroglie › Cellules de Schwann ›