Ascending colon cancer metastasized to the right testicle: a case report.
Ascending colon carcinoma
Case report
Hemicolectomy
Radical orchiectomy
Testicular metastasis
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
27 Jun 2024
27 Jun 2024
Historique:
received:
05
04
2024
accepted:
13
05
2024
medline:
27
6
2024
pubmed:
27
6
2024
entrez:
26
6
2024
Statut:
epublish
Résumé
Testicular metastasis from malignant solid tumors is extremely rare. It is usually found by chance during autopsy or pathological examination of testicular specimens. Therefore, we consider it necessary to report our patient's case of testicular metastasis from colon cancer. We report a 61-year-old Han Chinese male patient who presented to our clinic with progressive painless swelling of the right testicle for 2 years. Positron emission tomography-computed tomography scans showed increased 18F-fluorodeoxyglucose metabolism in the right testicle, possibly owing to distant metastasis. His previous medical history suggested that he had undergone laparoscopic-assisted right hemicolectomy for ascending colon cancer 4 years ago. Considering the ascending colon cancer metastasis to the right testicle, we performed a right radical testicular resection through an inguinal approach. Postoperative histological examination showed intestinal metastatic adenocarcinoma. Colon cancer metastasis to the testes is uncommon. The clinical and imaging manifestations of this tumor are nonspecific, so the diagnosis relies on postoperative pathology. If testicular metastasis is found, treatment principles for advanced colon cancer should be followed.
Sections du résumé
BACKGROUND
BACKGROUND
Testicular metastasis from malignant solid tumors is extremely rare. It is usually found by chance during autopsy or pathological examination of testicular specimens. Therefore, we consider it necessary to report our patient's case of testicular metastasis from colon cancer.
CASE PRESENTATION
METHODS
We report a 61-year-old Han Chinese male patient who presented to our clinic with progressive painless swelling of the right testicle for 2 years. Positron emission tomography-computed tomography scans showed increased 18F-fluorodeoxyglucose metabolism in the right testicle, possibly owing to distant metastasis. His previous medical history suggested that he had undergone laparoscopic-assisted right hemicolectomy for ascending colon cancer 4 years ago. Considering the ascending colon cancer metastasis to the right testicle, we performed a right radical testicular resection through an inguinal approach. Postoperative histological examination showed intestinal metastatic adenocarcinoma.
CONCLUSION
CONCLUSIONS
Colon cancer metastasis to the testes is uncommon. The clinical and imaging manifestations of this tumor are nonspecific, so the diagnosis relies on postoperative pathology. If testicular metastasis is found, treatment principles for advanced colon cancer should be followed.
Identifiants
pubmed: 38926771
doi: 10.1186/s13256-024-04587-z
pii: 10.1186/s13256-024-04587-z
doi:
Substances chimiques
Fluorodeoxyglucose F18
0Z5B2CJX4D
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
305Subventions
Organisme : Nanjing Medical Technology Development Project
ID : No. YKK23071
Organisme : Clinical Trials from the Affiliated Drum Tower Hospital, Medical School of Nanjing University
ID : No.2023-LCYJ-PY-41
Organisme : National Natural Science Foundation of China
ID : 82271649
Informations de copyright
© 2024. The Author(s).
Références
Stevenson SM, Lowrance WT. Epidemiology and diagnosis of testis cancer. Urol Clin N Am. 2015;42(3):269–75.
doi: 10.1016/j.ucl.2015.04.001
Tiltman AJ. Metastatic tumours in the testis. Histopathology. 1979;3(1):31–7.
doi: 10.1111/j.1365-2559.1979.tb02979.x
pubmed: 428920
Hatoum HA, Abi Saad GS, Otrock ZK, Barada KA, Shamseddine AI. Metastasis of colorectal carcinoma to the testes: clinical presentation and possible pathways. Int J Clin Oncol. 2011;16(3):203–9.
doi: 10.1007/s10147-010-0140-z
pubmed: 21069550
Gao Q, Chen J, Dai Y. Prostate cancer involving bilateral seminal vesicles along with bone and testicular metastases: a case report. J Med Case Rep. 2018;12(1):72.
doi: 10.1186/s13256-017-1551-5
pubmed: 29519246
pmcid: 5844096
Dusaud M, Adjadj L, Debelmas A, Souraud JB, Durand X. Malignant melanoma revealed by testicular metastasi. Int J Surg Case Rep. 2015;12:102–5.
doi: 10.1016/j.ijscr.2015.05.026
pubmed: 26048630
pmcid: 4486107
De Andrade JP, Warner SG, Fong Y. Treatment of metastatic colorectal cancer: innovations in surgical techniques. J Surg Oncol. 2019;119(5):653–9.
doi: 10.1002/jso.25418
pubmed: 30811033
Xu Q, Li XL, Yu YW, Dong LR, Shen JG, Wang LB. Right cryptorchid testicular metastasis from descending colon carcinoma: a case report of “Krukenberg tumor” in male. Asian J Androl. 2015;17(1):171–2.
doi: 10.4103/1008-682X.142769
pubmed: 25337848
Bunn R, Liu S, Stokes S, Turner J, Louie-Johnsun M. Mucinous lung adenocarcinoma metastasis to testis in a 29 year old—a case report. Urology. 2018;118:3–5.
doi: 10.1016/j.urology.2018.01.016
pubmed: 29548865
Al-Ali BM, Augustin H, Popper H, Pummer K. A case of descending colon carcinoma metastasized to left spermatic cord, testis, and epididymis. Cent Eur J Urol. 2012;65(2):94–5.
doi: 10.5173/ceju.2012.02.art10
Meacham RB, Mata JA, Espada R, Wheeler TM, Schum CW, Scardino PT. Testicular metastasis as the first manifestation of colon carcinoma. J Urol. 1988;140(3):621–2.
doi: 10.1016/S0022-5347(17)41740-X
pubmed: 3411689
Charles W, Joseph G, Hunis B, Rankin L. Metastatic colon cancer to the testicle presenting as testicular hydrocele. J Clin Oncol. 2005;23(22):5256–7.
doi: 10.1200/JCO.2005.06.109
pubmed: 16051969
Advani S, Kopetz S. Ongoing and future directions in the management of metastatic colorectal cancer: update on clinical trials. J Surg Oncol. 2019;119(5):642–52.
doi: 10.1002/jso.25441
pubmed: 30852840
Phillips JD, Hasson RM. Surgical management of colorectal lung metastases. J Surg Oncol. 2019;119(5):629–35.
doi: 10.1002/jso.25425
pubmed: 30811031