Dispersal history of SARS-CoV-2 in Galicia, Spain.
SARS‐CoV‐2
dispersal
phylogeography
variants of concern
Journal
Journal of medical virology
ISSN: 1096-9071
Titre abrégé: J Med Virol
Pays: United States
ID NLM: 7705876
Informations de publication
Date de publication:
Jul 2024
Jul 2024
Historique:
revised:
18
06
2024
received:
25
03
2024
accepted:
19
06
2024
medline:
28
6
2024
pubmed:
28
6
2024
entrez:
28
6
2024
Statut:
ppublish
Résumé
The dynamics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission are influenced by a variety of factors, including social restrictions and the emergence of distinct variants. In this study, we delve into the origins and dissemination of the Alpha, Delta, and Omicron-BA.1 variants of concern in Galicia, northwest Spain. For this, we leveraged genomic data collected by the EPICOVIGAL Consortium and from the GISAID database, along with mobility information from other Spanish regions and foreign countries. Our analysis indicates that initial introductions during the Alpha phase were predominantly from other Spanish regions and France. However, as the pandemic progressed, introductions from Portugal and the United States became increasingly significant. The number of detected introductions varied from 96 and 101 for Alpha and Delta to 39 for Omicron-BA.1. Most of these introductions left a low number of descendants (<10), suggesting a limited impact on the evolution of the pandemic in Galicia. Notably, Galicia's major coastal cities emerged as critical hubs for viral transmission, highlighting their role in sustaining and spreading the virus. This research emphasizes the critical role of regional connectivity in the spread of SARS-CoV-2 and offers essential insights for enhancing public health strategies and surveillance measures.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e29773Subventions
Organisme : Wellcome Trust
ID : 06298/Z/17/Z
Pays : United Kingdom
Organisme : NIH HHS
ID : R01 AI153044
Pays : United States
Organisme : NIH HHS
ID : R01 AI162611
Pays : United States
Organisme : NIH HHS
ID : U19 AI135995
Pays : United States
Organisme : European Union Horizon 2020 project MOOD
ID : 874850
Organisme : European Union's Horizon 2020 Research and Innovation Programme
ID : 725422-ReservoirDOCS
Organisme : Foundation for Science and Technology
ID : UIDB/50026/2020
Organisme : Foundation for Science and Technology
ID : UIDP/50026/2020
Organisme : Banco Santander-CSIC-CRUE
ID : EPICOVIGAL FONDO SUPERA-COVID19
Organisme : Fonds National de la Recherche Scientifique
ID : F.4515.22
Organisme : Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia
Organisme : Consellería de Sanidade, Xunta de Galicia
Organisme : DURABLE EU4Health
ID : 02/2023-01/2027
Organisme : European Union Horizon RIA 2023 project LEAPS
ID : 101094685
Organisme : Research Foundation - Flanders
ID : G098321N
Organisme : KU Leuven
ID : C14/18/094
Informations de copyright
© 2024 The Author(s). Journal of Medical Virology published by Wiley Periodicals LLC.
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