Ventrointermediate thalamic stimulation improves motor learning in humans.


Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
02 Jul 2024
Historique:
received: 22 09 2023
accepted: 15 06 2024
medline: 3 7 2024
pubmed: 3 7 2024
entrez: 2 7 2024
Statut: epublish

Résumé

Ventrointermediate thalamic stimulation (VIM-DBS) modulates oscillatory activity in a cortical network including primary motor cortex, premotor cortex, and parietal cortex. Here we show that, beyond the beneficial effects of VIM-DBS on motor execution, this form of invasive stimulation facilitates production of sequential finger movements that follow a repeated sequence. These results highlight the role of thalamo-cortical activity in motor learning.

Identifiants

pubmed: 38956172
doi: 10.1038/s42003-024-06462-5
pii: 10.1038/s42003-024-06462-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

798

Subventions

Organisme : Deutsche Forschungsgemeinschaft (German Research Foundation)
ID : SW 214/2-1
Organisme : Deutsche Forschungsgemeinschaft (German Research Foundation)
ID : SW 214/2-1

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Angela Voegtle (A)

Neurocybernetics and Rehabilitation, Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany. angela.voegtle@med.ovgu.de.

Laila Terzic (L)

Neurocybernetics and Rehabilitation, Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Amr Farahat (A)

Neurocybernetics and Rehabilitation, Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Ernst Strüngmann Institute for Neuroscience in Cooperation with Max Planck Society, Frankfurt am Main, Germany.

Nanna Hartong (N)

Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Imke Galazky (I)

Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Hermann Hinrichs (H)

Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Department of Behavioral Neurology, Leibniz Institute for Neurobiology, Magdeburg, Germany.
Center for Behavioral Brain Sciences-CBBS, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Slawomir J Nasuto (SJ)

Biomedical Sciences and Biomedical Engineering Division, School of Biological Sciences, University of Reading, Reading, UK.

Adriano de Oliveira Andrade (A)

Faculty of Electrical Engineering, Center for Innovation and Technology Assessment in Health, Postgraduate Program in Electrical and Biomedical Engineering, Federal University of Uberlândia, Uberlândia, Brazil.

Robert T Knight (RT)

Helen Wills Neuroscience Institute, University of California-Berkeley, Berkeley, CA, USA.

Richard B Ivry (RB)

Helen Wills Neuroscience Institute, University of California-Berkeley, Berkeley, CA, USA.
Department of Psychology, University of California-Berkeley, Berkeley, CA, USA.

Jürgen Voges (J)

Department of Stereotactic Neurosurgery, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Matthias Deliano (M)

Combinatorial Neuroimaging Core Facility, Leibniz Institute for Neurobiology, Magdeburg, Germany.

Lars Buentjen (L)

Department of Stereotactic Neurosurgery, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Catherine M Sweeney-Reed (CM)

Neurocybernetics and Rehabilitation, Department of Neurology, Otto von Guericke University Magdeburg, Magdeburg, Germany. catherine.sweeney-reed@med.ovgu.de.
Center for Behavioral Brain Sciences-CBBS, Otto von Guericke University Magdeburg, Magdeburg, Germany. catherine.sweeney-reed@med.ovgu.de.

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