Long-term health outcomes from inbreeding in a historical Swedish population: longevity, fertility, and impairments.
Human inbreeding
consanguinity
fertility
impairment
longevity
Journal
Annals of human biology
ISSN: 1464-5033
Titre abrégé: Ann Hum Biol
Pays: England
ID NLM: 0404024
Informations de publication
Date de publication:
Feb 2024
Feb 2024
Historique:
medline:
9
7
2024
pubmed:
9
7
2024
entrez:
9
7
2024
Statut:
ppublish
Résumé
Inbreeding, arising from consanguinity between related parents, has been observed to impact the health of individuals, typically attributed to biological factors. Nevertheless, these effects may be influenced by the social and environmental conditions. The prevalence of consanguineous marriages increased in certain parts of Sweden after it became legal in 1844, which offers a unique opportunity to study and understand the effects of inbreeding on health. The objective of this study is to explore the potential impact of inbreeding on the longevity, fertility, and impairments of individuals born in the Skellefteå region, Sweden, between 1890 and 1905, with a follow-up period extending until 1950. The level of inbreeding is calculated using micro-level parish register data and related to longevity, fertility, and impairments using regression analysis. Inbreeding is shown to be associated with longevity, fertility, and impairments. It seems to affect the risk of stillbirth and impairments and male longevity and fertility. Inbreeding seems to have had a detrimental effect on some health outcomes in this historical population under study.
Sections du résumé
BACKGROUND
UNASSIGNED
Inbreeding, arising from consanguinity between related parents, has been observed to impact the health of individuals, typically attributed to biological factors. Nevertheless, these effects may be influenced by the social and environmental conditions. The prevalence of consanguineous marriages increased in certain parts of Sweden after it became legal in 1844, which offers a unique opportunity to study and understand the effects of inbreeding on health.
AIM
UNASSIGNED
The objective of this study is to explore the potential impact of inbreeding on the longevity, fertility, and impairments of individuals born in the Skellefteå region, Sweden, between 1890 and 1905, with a follow-up period extending until 1950.
SUBJECTS AND METHODS
UNASSIGNED
The level of inbreeding is calculated using micro-level parish register data and related to longevity, fertility, and impairments using regression analysis.
RESULTS
UNASSIGNED
Inbreeding is shown to be associated with longevity, fertility, and impairments. It seems to affect the risk of stillbirth and impairments and male longevity and fertility.
CONCLUSION
UNASSIGNED
Inbreeding seems to have had a detrimental effect on some health outcomes in this historical population under study.
Identifiants
pubmed: 38979927
doi: 10.1080/03014460.2024.2369281
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM