Association of Perinatal Cardiovascular Features with Angiotensin System Expressions in Maternal Preeclampsia.
aminopeptidase-N
angiotensin II receptors
blood pressure
cardiovascular
coronary artery
developmental origin of health and disease
neonate
offspring
perinatal
preeclampsia
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
06 Jul 2024
06 Jul 2024
Historique:
received:
28
05
2024
revised:
28
06
2024
accepted:
02
07
2024
medline:
13
7
2024
pubmed:
13
7
2024
entrez:
13
7
2024
Statut:
epublish
Résumé
We hypothesized and investigated whether prenatal exposure to preeclampsia (PE) would simultaneously affect perinatal cardiovascular features and angiotensin system expressions. This prospective study was composed of mother-neonate dyads with (n = 49) and without maternal preeclampsia (n = 48) in a single tertiary medical center. The neonates exposed to PE had significantly larger relative sizes for the left and right coronary arteries and a higher cord plasma level of aminopeptidase-N, which positively correlated with the maternal diastolic blood pressures and determined the relative sizes of the left and right coronary arteries, whereas the encoding aminopeptidase-N (
Identifiants
pubmed: 39000532
pii: ijms25137426
doi: 10.3390/ijms25137426
pii:
doi:
Substances chimiques
Receptor, Angiotensin, Type 1
0
RNA, Messenger
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Kaohsiung Chang Gung Memorial Hospital
ID : CMRPG8I0421
Organisme : Kaohsiung Chang Gung Memorial Hospital
ID : CMRPG8L1532