Immune-related colitis presenting with constipation.

Humans Constipation / etiology Colitis / immunology Male Female Middle Aged Aged Delayed Diagnosis
Gastrointestinal system Oncology Unwanted effects / adverse reactions

Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
22 Jul 2024
Historique:
medline: 23 7 2024
pubmed: 23 7 2024
entrez: 22 7 2024
Statut: epublish

Résumé

Anticancer immunotherapies modulate the body's immune system to recognise and eradicate cancerous cells. However, stimulation of the body's immune system can also lead to a number of adverse effects when those immune cells target non-cancerous cells in the form of autoimmunity. One relatively common example of this off-target action is colitis.We present three patients who presented atypically with colitis, consequently, leading to a delayed diagnosis. These cases highlight the diverse ways a relatively common immune-related adverse event can present.

Identifiants

DOI: 10.1136/bcr-2023-258940 PMID: 39038878
pubmed: 39038878
pii: 17/7/e258940
doi: 10.1136/bcr-2023-258940
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Athanasios Malkopoulos (A)

Queensland Health, Brisbane, Queensland, Australia thano.malkopoulos@health.qld.gov.au.

Robert Mason (R)

Queensland Health, Brisbane, Queensland, Australia.

Sooraj Pillai (S)

Queensland Health, Brisbane, Queensland, Australia.

Marcin Dzienis (M)

Queensland Health, Brisbane, Queensland, Australia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Immune-related colitis presenting with constipation.
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Signes et symptômes digestifs › Constipation › Immune-related colitis presenting with constipation.
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Colite › Immune-related colitis presenting with constipation.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Immune-related colitis presenting with constipation.
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Immune-related colitis presenting with constipation.
questionsmedicales.fr › Établissements, main d'oeuvre et services de soins de santé › Services de santé › Soins aux patients › Retard de diagnostic › Immune-related colitis presenting with constipation.