Impact of OATP2B1 on pharmacokinetics of atorvastatin investigated in
Organic anion uptake / efflux (OATs, OATPs)
drug transport
genetically modified animal models
pharmacokinetics
Journal
Drug metabolism and disposition: the biological fate of chemicals
ISSN: 1521-009X
Titre abrégé: Drug Metab Dispos
Pays: United States
ID NLM: 9421550
Informations de publication
Date de publication:
22 Jul 2024
22 Jul 2024
Historique:
accepted:
21
06
2024
received:
02
02
2024
revised:
05
06
2024
medline:
23
7
2024
pubmed:
23
7
2024
entrez:
22
7
2024
Statut:
aheadofprint
Résumé
The organic anion transporting polypeptide (OATP) 2B1 is considered an emerging drug transporter that is found expressed in pharmacokinetically relevant organs such as the liver, small intestine, and kidney. Despite its interaction with various substrate drugs, the understanding of its
Identifiants
pubmed: 39038952
pii: dmd.124.001686
doi: 10.1124/dmd.124.001686
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 American Society for Pharmacology and Experimental Therapeutics.