Daniel Ricklin

Affiliations

Department of Pharmaceutical Sciences, University of Basel, Klingelbergstrasse 50, 4056, Basel, Switzerland.

Publications (27)

Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside.

ChemMedChem

Avec: Benedetta Girardi , Martina Manna , Sjors Van Klaveren , Tihomir Tomašič , Žiga Jakopin , Hakon Leffler , Ulf J Nilsson , Daniel Ricklin , Janez Mravljak , Oliver Schwardt , Marko Anderluh

Impact of OATP2B1 on pharmacokinetics of atorvastatin investigated in

Drug metabolism and disposition: the biological fate of chemicals

Avec: Jonny Kinzi , Janine Hussner , Isabell Seibert , Mirubagini Vythilingam , Celina Vonwyl , Clarisse Gherardi , Pascal Detampel , Oliver Schwardt , Daniel Ricklin , Henriette E Meyer Zu Schwabedissen

Humanization of

The Journal of pharmacology and experimental therapeutics

Avec: Marta Rysz , Anima M Schäfer , Nikolaos Paloumpis , Jonny Kinzi , Karin Brecht , Isabell Seibert , Seraina Schmidlin , Katja In-Albon , Daniel Ricklin , Henriette E Meyer Zu Schwabedissen

Prolonged intraocular residence and retinal tissue distribution of a fourth-generation compstatin-based C3 inhibitor in non-human primates.

Clinical immunology (Orlando, Fla.)

Avec: Sarah Hughes , Justin Gumas , Rebecca Lee , Merita Rumano , Nadja Berger , Avneesh Kumar Gautam , Georgia Sfyroera , Anna Lorena Chan , Gopalan Gnanaguru , Kip M Connor , Benjamin J Kim , Joshua L Dunaief , Daniel Ricklin , George Hajishengallis , Despina Yancopoulou , Edimara S Reis , Dimitrios C Mastellos , John D Lambris

Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces.

Frontiers in immunology

Avec: Arthur Dopler , Selina Stibitzky , Rachel Hevey , Marco Mannes , Mara Guariento , Britta Höchsmann , Hubert Schrezenmeier , Daniel Ricklin , Christoph Q Schmidt

Sweet turning bitter: Carbohydrate sensing of complement in host defence and disease.

British journal of pharmacology

Avec: Rachel Hevey , Richard B Pouw , Claire Harris , Daniel Ricklin

Factor H interferes with the adhesion of sickle red cells to vascular endothelium: a novel disease-modulating molecule.

Haematologica

Avec: Elisabetta Lombardi , Alessandro Matte , Antonio M Risitano , Daniel Ricklin , John D Lambris , Denise De Zanet , Sakari T Jokiranta , Nicola Martinelli , Cinzia Scambi , Gianluca Salvagno , Zeno Bisoffi , Chiara Colato , Angela Siciliano , Oscar Bortolami , Mario Mazzuccato , Francesco Zorzi , Luigi De Marco , Lucia De Franceschi

The Promiscuous Profile of Complement Receptor 3 in Ligand Binding, Immune Modulation, and Pathophysiology.

Frontiers in immunology

Avec: Christina Lamers , Carla Johanna Plüss , Daniel Ricklin

Therapeutic Peptides as Emerging Options to Restore Misguided Host Defence and Homeostasis: From Teaching to Concept to Clinic.

Chimia

Avec: Oliver Schwardt , Christina Lamers , Clément Bechtler , Daniel Ricklin

Tetra- and Hexavalent Siglec-8 Ligands Modulate Immune Cell Activation.

Angewandte Chemie (International ed. in English)

Avec: Gabriele Conti , Anne Bärenwaldt , Said Rabbani , Tobias Mühlethaler , Mirza Sarcevic , Xiaohua Jiang , Oliver Schwardt , Daniel Ricklin , Roland J Pieters , Heinz Läubli , Beat Ernst

Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.

Nature communications

Avec: Christina Lamers , Xiaoguang Xue , Martin Smieško , Henri van Son , Bea Wagner , Nadja Berger , Georgia Sfyroera , Piet Gros , John D Lambris , Daniel Ricklin

Complement-targeted therapeutics: An emerging field enabled by academic drug discovery.

American journal of hematology

Avec: Christina Lamers , Daniel Ricklin , John D Lambris

Optimized synthesis, polymer conjugation, and proof-of-concept studies of the gd-IgA1 epitope for antibody-scavenging therapies in IgA nephropathy.

Chemical biology & drug design

Avec: Clément Bechtler , Ouliana Barneoud-Rousset , Lijuan Pang , Kea Martin , Katrin F König , Pascal Hänggi , Nick Pearson , Daniel Ricklin

Tipping the balance: intricate roles of the complement system in disease and therapy.

Seminars in immunopathology

Avec: Richard B Pouw , Daniel Ricklin

Intracellular C4BPA Levels Regulate NF-κB-Dependent Apoptosis.

iScience

Avec: Monica M Olcina , Ryan K Kim , Nikolas G Balanis , Caiyun Grace Li , Rie von Eyben , Thomas G Graeber , Daniel Ricklin , Manuel Stucki , Amato J Giaccia

Compstatins: the dawn of clinical C3-targeted complement inhibition.

Trends in pharmacological sciences

Avec: Christina Lamers , Dimitrios C Mastellos , Daniel Ricklin , John D Lambris

Exploring the function of factor XIII free B subunit: Interactions with complement factors and a novel approach to identify potential binding partners.

Research and practice in thrombosis and haemostasis

Avec: Bojun Li , Clément Bechtler , Lorenz Jenny , Daniel Ricklin , Verena Schroeder

A Potent Mimetic of the Siglec-8 Ligand 6'-Sulfo-Sialyl Lewis

ChemMedChem

Avec: Blijke S Kroezen , Gabriele Conti , Benedetta Girardi , Jonathan Cramer , Xiaohua Jiang , Said Rabbani , Jennifer Müller , Maja Kokot , Enrico Luisoni , Daniel Ricklin , Oliver Schwardt , Beat Ernst

Clinical promise of next-generation complement therapeutics.

Nature reviews. Drug discovery

Avec: Dimitrios C Mastellos , Daniel Ricklin , John D Lambris

Protective Effects of the Complement Inhibitor Compstatin CP40 in Hemorrhagic Shock.

Shock (Augusta, Ga.)

Avec: Martijn van Griensven , Daniel Ricklin , Stephanie Denk , Rebecca Halbgebauer , Christian K Braun , Anke Schultze , Felix Hönes , Sofia Koutsogiannaki , Alexandra Primikyri , Edimara Reis , David Messerer , Sebastian Hafner , Peter Radermacher , Ali-Reza Biglarnia , Ranillo R G Resuello , Joel V Tuplano , Benjamin Mayer , Kristina Nilsson , Bo Nilsson , John D Lambris , Markus Huber-Lang

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development.

Nature immunology

Avec: Dimitrios C Mastellos , Anna M Blom , E Sander Connolly , Mohamed R Daha , Brian V Geisbrecht , Berhane Ghebrehiwet , Piet Gros , George Hajishengallis , V Michael Holers , Markus Huber-Lang , Taroh Kinoshita , Tom E Mollnes , Robert A Montgomery , B Paul Morgan , Bo Nilsson , Ruben Pio , Daniel Ricklin , Antonio M Risitano , Ronald P Taylor , Alberto Mantovani , John P A Ioannidis , John D Lambris

C1q binding to surface-bound IgG is stabilized by C1r

Proceedings of the National Academy of Sciences of the United States of America

Avec: Seline A Zwarthoff , Kevin Widmer , Annemarie Kuipers , Jürgen Strasser , Maartje Ruyken , Piet C Aerts , Carla J C de Haas , Deniz Ugurlar , Maurits A den Boer , Gestur Vidarsson , Jos A G van Strijp , Piet Gros , Paul W H I Parren , Kok P M van Kessel , Johannes Preiner , Frank J Beurskens , Janine Schuurman , Daniel Ricklin , Suzan H M Rooijakkers

From discovery to approval: A brief history of the compstatin family of complement C3 inhibitors.

Clinical immunology (Orlando, Fla.)

Avec: Dimitrios C Mastellos , Daniel Ricklin , Georgia Sfyroera , Arvind Sahu

Complement-regulatory biomaterial coatings: Activity and selectivity profile of the factor H-binding peptide 5C6.

Acta biomaterialia

Avec: Clément Bechtler , Sophia Koutsogiannaki , Ekaterina Umnyakova , Amal Hamid , Avneesh Gautam , Yiannis Sarigiannis , Richard B Pouw , Christina Lamers , Said Rabbani , Christoph Q Schmidt , John D Lambris , Daniel Ricklin

Complement inhibition can decrease the haemostatic response in a microvascular bleeding model at multiple levels.

Frontiers in immunology

Avec: Murielle Golomingi , Jessie Kohler , Christina Lamers , Richard B Pouw , Daniel Ricklin , József Dobó , Péter Gál , Gábor Pál , Bence Kiss , Arthur Dopler , Christoph Q Schmidt , Elaissa Trybus Hardy , Wilbur Lam , Verena Schroeder

Simultaneous quantification of atorvastatin, erlotinib and OSI-420 in rat serum and liver microsomes using a novel liquid chromatography-mass spectrometry method.

Journal of pharmaceutical and biomedical analysis

Avec: Marta A Rysz , Jonny Kinzi , Anima M Schäfer , Katja In-Albon , Simone Zürcher , Seraina Schmidlin , Isabell Seibert , Oliver Schwardt , Daniel Ricklin , Henriette E Meyer Zu Schwabedissen

Complement-targeted therapeutics: Are we there yet, or just getting started?

European journal of immunology

Avec: Daniel Ricklin

Réseau de co-auteurs

John D Lambris 9 collaborations

Christina Lamers 7 collaborations

Oliver Schwardt 6 collaborations

Dimitrios C Mastellos 5 collaborations

Richard B Pouw 4 collaborations

Clément Bechtler 4 collaborations

Jonny Kinzi 3 collaborations

Isabell Seibert 3 collaborations

Henriette E Meyer Zu Schwabedissen 3 collaborations

Georgia Sfyroera 3 collaborations

Christoph Q Schmidt 3 collaborations

Said Rabbani 3 collaborations

Piet Gros 3 collaborations

Benedetta Girardi 2 collaborations

Anima M Schäfer 2 collaborations

Seraina Schmidlin 2 collaborations

Katja In-Albon 2 collaborations

Nadja Berger 2 collaborations

George Hajishengallis 2 collaborations

Arthur Dopler 2 collaborations

Rachel Hevey 2 collaborations

Antonio M Risitano 2 collaborations

Gabriele Conti 2 collaborations

Xiaohua Jiang 2 collaborations

Beat Ernst 2 collaborations

Verena Schroeder 2 collaborations

Bo Nilsson 2 collaborations

Markus Huber-Lang 2 collaborations

Martina Manna 1 collaboration

Sjors Van Klaveren 1 collaboration

Tihomir Tomašič 1 collaboration

Žiga Jakopin 1 collaboration

Hakon Leffler 1 collaboration

Ulf J Nilsson 1 collaboration

Janez Mravljak 1 collaboration

Marko Anderluh 1 collaboration

Janine Hussner 1 collaboration

Mirubagini Vythilingam 1 collaboration

Celina Vonwyl 1 collaboration

Clarisse Gherardi 1 collaboration

Pascal Detampel 1 collaboration

Marta Rysz 1 collaboration

Nikolaos Paloumpis 1 collaboration

Karin Brecht 1 collaboration

Sarah Hughes 1 collaboration

Justin Gumas 1 collaboration

Rebecca Lee 1 collaboration

Merita Rumano 1 collaboration

Avneesh Kumar Gautam 1 collaboration

Anna Lorena Chan 1 collaboration

Gopalan Gnanaguru 1 collaboration

Kip M Connor 1 collaboration

Benjamin J Kim 1 collaboration

Joshua L Dunaief 1 collaboration

Despina Yancopoulou 1 collaboration

Edimara S Reis 1 collaboration

Selina Stibitzky 1 collaboration

Marco Mannes 1 collaboration

Mara Guariento 1 collaboration

Britta Höchsmann 1 collaboration

Hubert Schrezenmeier 1 collaboration

Claire Harris 1 collaboration

Elisabetta Lombardi 1 collaboration

Alessandro Matte 1 collaboration

Denise De Zanet 1 collaboration

Sakari T Jokiranta 1 collaboration

Nicola Martinelli 1 collaboration

Cinzia Scambi 1 collaboration

Gianluca Salvagno 1 collaboration

Zeno Bisoffi 1 collaboration

Chiara Colato 1 collaboration

Angela Siciliano 1 collaboration

Oscar Bortolami 1 collaboration

Mario Mazzuccato 1 collaboration

Francesco Zorzi 1 collaboration

Luigi De Marco 1 collaboration

Lucia De Franceschi 1 collaboration

Carla Johanna Plüss 1 collaboration

Anne Bärenwaldt 1 collaboration

Tobias Mühlethaler 1 collaboration

Mirza Sarcevic 1 collaboration

Roland J Pieters 1 collaboration

Heinz Läubli 1 collaboration

Xiaoguang Xue 1 collaboration

Martin Smieško 1 collaboration

Henri van Son 1 collaboration

Bea Wagner 1 collaboration

Ouliana Barneoud-Rousset 1 collaboration

Lijuan Pang 1 collaboration

Kea Martin 1 collaboration

Katrin F König 1 collaboration

Pascal Hänggi 1 collaboration

Nick Pearson 1 collaboration

Monica M Olcina 1 collaboration

Ryan K Kim 1 collaboration

Nikolas G Balanis 1 collaboration

Caiyun Grace Li 1 collaboration

Rie von Eyben 1 collaboration

Thomas G Graeber 1 collaboration

Manuel Stucki 1 collaboration

Amato J Giaccia 1 collaboration

Bojun Li 1 collaboration

Lorenz Jenny 1 collaboration

Blijke S Kroezen 1 collaboration

Jonathan Cramer 1 collaboration

Jennifer Müller 1 collaboration

Maja Kokot 1 collaboration

Enrico Luisoni 1 collaboration

Martijn van Griensven 1 collaboration

Stephanie Denk 1 collaboration

Rebecca Halbgebauer 1 collaboration

Christian K Braun 1 collaboration

Anke Schultze 1 collaboration

Felix Hönes 1 collaboration

Sofia Koutsogiannaki 1 collaboration

Alexandra Primikyri 1 collaboration

Edimara Reis 1 collaboration

David Messerer 1 collaboration

Sebastian Hafner 1 collaboration

Peter Radermacher 1 collaboration

Ali-Reza Biglarnia 1 collaboration

Ranillo R G Resuello 1 collaboration

Joel V Tuplano 1 collaboration

Benjamin Mayer 1 collaboration

Kristina Nilsson 1 collaboration

Anna M Blom 1 collaboration

E Sander Connolly 1 collaboration

Mohamed R Daha 1 collaboration

Brian V Geisbrecht 1 collaboration

Berhane Ghebrehiwet 1 collaboration

V Michael Holers 1 collaboration

Taroh Kinoshita 1 collaboration

Tom E Mollnes 1 collaboration

Robert A Montgomery 1 collaboration

B Paul Morgan 1 collaboration

Ruben Pio 1 collaboration

Ronald P Taylor 1 collaboration

Alberto Mantovani 1 collaboration

John P A Ioannidis 1 collaboration

Seline A Zwarthoff 1 collaboration

Kevin Widmer 1 collaboration

Annemarie Kuipers 1 collaboration

Jürgen Strasser 1 collaboration

Maartje Ruyken 1 collaboration

Piet C Aerts 1 collaboration

Carla J C de Haas 1 collaboration

Deniz Ugurlar 1 collaboration

Maurits A den Boer 1 collaboration

Gestur Vidarsson 1 collaboration

Jos A G van Strijp 1 collaboration

Paul W H I Parren 1 collaboration

Kok P M van Kessel 1 collaboration

Johannes Preiner 1 collaboration

Frank J Beurskens 1 collaboration

Janine Schuurman 1 collaboration

Suzan H M Rooijakkers 1 collaboration

Arvind Sahu 1 collaboration

Sophia Koutsogiannaki 1 collaboration

Ekaterina Umnyakova 1 collaboration

Amal Hamid 1 collaboration

Avneesh Gautam 1 collaboration

Yiannis Sarigiannis 1 collaboration

Murielle Golomingi 1 collaboration

Jessie Kohler 1 collaboration

József Dobó 1 collaboration

Péter Gál 1 collaboration

Gábor Pál 1 collaboration

Bence Kiss 1 collaboration

Elaissa Trybus Hardy 1 collaboration

Wilbur Lam 1 collaboration

Marta A Rysz 1 collaboration

Simone Zürcher 1 collaboration