The effects of mitral stenosis on right ventricular mechanics assessed by three-dimensional echocardiography.
Atrial fibrillation
Contraction pattern
Mitral stenosis
Right ventricle
Speckle-tracking echocardiography
Three-dimensional echocardiography
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
24 Jul 2024
24 Jul 2024
Historique:
received:
11
02
2024
accepted:
19
07
2024
medline:
26
7
2024
pubmed:
26
7
2024
entrez:
24
7
2024
Statut:
epublish
Résumé
Mitral stenosis (MS) is a complex valvular pathology with significant clinical burden even today. Its effect on the right heart is often overlooked, despite it playing a considerable part in the symptomatic status. We enrolled 39 mitral valve stenosis patients and 39 age- and gender-matched healthy controls. They underwent conventional, speckle-tracking and 3D echocardiographic examinations. The 3D data was analyzed using the ReVISION software to calculate RV functional parameters. In the MS group, 3D RV ejection fraction (EF) (49 ± 7% vs. 61 ± 4%; p < 0.001), global circumferential (GCS) (- 21.08 ± 5.64% vs. - 25.07 ± 4.72%; p = 0.001) and longitudinal strain (GLS) (- 16.60% ± 4.07% vs. - 23.32 ± 2.82%; p < 0.001) were reduced. When comparing RV contraction patterns between controls, MS patients in sinus rhythm and those with atrial fibrillation, radial (REF) (32.06 ± 5.33% vs. 23.62 ± 7.95% vs. 20.89 ± 6.92%; p < 0.001) and longitudinal ejection fraction (LEF) (24.85 ± 4.06%; 17.82 ± 6.16% vs. 15.91 ± 4.09%; p < 0.001) were decreased in both MS groups compared to controls; however, they were comparable between the two MS subgroups. Anteroposterior ejection fraction (AEF) (29.16 ± 4.60% vs. 30.87 ± 7.71% vs. 21.48 ± 6.15%; p < 0.001) showed no difference between controls and MS patients in sinus rhythm, while it was lower in the MS group with atrial fibrillation. Therefore, utilizing 3D echocardiography, we found distinct morphological and functional alterations of the RV in MS patients.
Identifiants
pubmed: 39048660
doi: 10.1038/s41598-024-68126-y
pii: 10.1038/s41598-024-68126-y
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
17112Subventions
Organisme : Innovációs és Technológiai Minisztérium
ID : ÚNKP-23-3-I-SE-64
Organisme : Innovációs és Technológiai Minisztérium
ID : ÚNKP-23-4-II-SE-37
Organisme : Innovációs és Technológiai Minisztérium
ID : TKP2021-EGA-23
Organisme : European Union
ID : RRF-2.3.1-21-2022-00003
Organisme : Magyar Tudományos Akadémia
ID : Janos Bolyai Research Scholarship
Informations de copyright
© 2024. The Author(s).
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