Update on Maintenance Immunosuppression in Intestinal Transplantation.


Journal

Gastroenterology clinics of North America
ISSN: 1558-1942
Titre abrégé: Gastroenterol Clin North Am
Pays: United States
ID NLM: 8706257

Informations de publication

Date de publication:
Sep 2024
Historique:
medline: 28 7 2024
pubmed: 28 7 2024
entrez: 27 7 2024
Statut: ppublish

Résumé

Outcomes in intestinal transplantation remain hampered by higher rates of rejection than any other solid organs. However, maintenance immunosuppression regimens have largely remained unchanged despite advances in therapies for induction and treatment of rejection and graft-versus-host disease. Recently, there have been a small number of new maintenance therapies attempted, and older agents have been used in new ways to achieve better outcomes. The authors herein review the traditional maintenance therapies and their mechanisms and then consider updates in new therapies and new ways of using old therapies for maintenance immunosuppression after intestinal transplantation.

Identifiants

pubmed: 39068010
pii: S0889-8553(23)00130-9
doi: 10.1016/j.gtc.2023.12.007
pii:
doi:

Substances chimiques

Immunosuppressive Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

493-507

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors declare no commercial or financial conflicts of interest.

Auteurs

Satyajit Patwardhan (S)

Columbia Center for Translational Immunology, 650 West 168th Street, BB1705, New York, NY 10032, USA.

Julie Hong (J)

Columbia Center for Translational Immunology, 650 West 168th Street, BB1705, New York, NY 10032, USA.

Joshua Weiner (J)

Columbia Center for Translational Immunology, 650 West 168th Street, BB1705, New York, NY 10032, USA; Division of Abdominal Organ Transplantation, Columbia University Irving Medical Center, 622 West 168th Street, PH14-105, New York, NY 10032, USA. Electronic address: jiw2106@cumc.columbia.edu.

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Classifications MeSH