Applications of Flow Cytometry in Diagnosis and Evaluation of Red Blood Cell Disorders.

Humans Flow Cytometry / methods Spherocytosis, Hereditary / diagnosis Erythrocytes / cytology Hemoglobinuria, Paroxysmal / diagnosis Hematologic Diseases / diagnosis Pregnancy Female Fetomaternal Transfusion / diagnosis
Band 3 Fetal–maternal hemorrhage Flow cytometry Paroxysmal nocturnal hemoglobinuria Red blood cell disorder

Journal

Clinics in laboratory medicine
ISSN: 1557-9832
Titre abrégé: Clin Lab Med
Pays: United States
ID NLM: 8100174

Informations de publication

Date de publication:
Sep 2024
Historique:
medline: 2 8 2024
pubmed: 2 8 2024
entrez: 1 8 2024
Statut: ppublish

Résumé

Clinical flow cytometry plays a vital role in the diagnosis and monitoring of various red blood cell disorders. The high throughput, precision, and automation potential of this technique allows for cost-effective and timely analysis compared to older and more manual test methods. Flow cytometric analysis serves as the gold standard diagnostic method for multiple hematological disorders, especially in clinical scenarios where an assay needs to have high sensitivity, high specificity, and a short turnaround time. In this review, we discuss the role of flow cytometric analysis in paroxysmal nocturnal hemoglobinuria, fetal-maternal hemorrhage, and hereditary spherocytosis.

Identifiants

DOI: 10.1016/j.cll.2024.04.010 PMID: 39089754
pubmed: 39089754
pii: S0272-2712(24)00021-0
doi: 10.1016/j.cll.2024.04.010
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

495-509

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure Authors have nothing to disclose.

Auteurs

Alexis Dadelahi (A)

Department of Pathology, University of Utah, 15 N. Medical Drive East, Suite 1100, Salt Lake City, UT 84112, USA; ARUP Laboratories, Salt Lake City, UT, USA.

Taylor Jackson (T)

Department of Pathology, University of Utah, 15 N. Medical Drive East, Suite 1100, Salt Lake City, UT 84112, USA; ARUP Laboratories, Salt Lake City, UT, USA.

Archana M Agarwal (AM)

Department of Pathology, University of Utah, 15 N. Medical Drive East, Suite 1100, Salt Lake City, UT 84112, USA; Special Hematology, ARUP Laboratories, Salt Lake City, UT, USA; Hematopathology, ARUP Laboratories, Salt Lake City, UT, USA.

Leo Lin (L)

Department of Pathology, University of Utah, 15 N. Medical Drive East, Suite 1100, Salt Lake City, UT 84112, USA; Research and Innovation, ARUP Laboratories, Salt Lake City, UT, USA; Immunologic Flow Cytometry, ARUP Laboratories, Salt Lake City, UT, USA; Immunology, ARUP Laboratories, Salt Lake City, UT, USA; PharmaDx, Research & Innovation ARUP Laboratories, 500 Chipeta Way, MS 115, Salt Lake City, UT 84108, USA.

Anton V Rets (AV)

Department of Pathology, University of Utah, 15 N. Medical Drive East, Suite 1100, Salt Lake City, UT 84112, USA; Hematopathology, ARUP Laboratories, Salt Lake City, UT, USA; Immunohistochemistry and Histology, ARUP Laboratories, Salt Lake City, UT, USA.

David P Ng (DP)

Department of Pathology, University of Utah, 15 N. Medical Drive East, Suite 1100, Salt Lake City, UT 84112, USA; Hematopathology, ARUP Laboratories, Salt Lake City, UT, USA; Applied Artificial Intelligence and Bioinformatics, ARUP Laboratories, Salt Lake City, UT, USA; Hematologic Flow Cytometry, ARUP Laboratories, Salt Lake City, UT, USA. Electronic address: david.ng@aruplab.com.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytophotométrie › Cytométrie en flux › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies génétiques congénitales › Anémie hémolytique congénitale › Sphérocytose héréditaire › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Sang › Cellules sanguines › Érythrocytes › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Maladies de la moelle osseuse › Syndromes myélodysplasiques › Hémoglobinurie paroxystique › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Hémopathies et maladies lymphatiques › Hémopathies › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Grossesse › Applications of Flow Cytometry in Diagnosis...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies néonatales › Anémie néonatale › Transfusion foetomaternelle › Applications of Flow Cytometry in Diagnosis...