Serum levels of biomarkers related to severity staging of Raynaud's phenomenon, neurosensory manifestations, and vibration exposure in patients with hand-arm vibration injury.
Aβ fibers
Aδ fibers
C-fibers
Cold intolerance
Endothelial dysfunction
Grading of injury
Hand-arm vibration syndrome (HAVS)
Neuroprotection
Occupational
Serum biomarkers
Vibration exposure
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
05 Aug 2024
05 Aug 2024
Historique:
received:
12
03
2024
accepted:
29
07
2024
medline:
6
8
2024
pubmed:
6
8
2024
entrez:
5
8
2024
Statut:
epublish
Résumé
Our aim was to explore possible relationships between serum levels of biomarkers in patients with hand-arm vibration injury in relation to the severity of the vascular, i.e., Raynaud's phenomenon (RP), and neurosensory manifestations, the current exposure level, and the duration of exposure. This study was of case series design and involved 92 patients diagnosed with hand-arm vibration injury. Jonckheere's trend test was used to assess any association between serum levels of biomarkers and RP as well as neurosensory manifestations, graded by the International Consensus Criteria. Generalized linear models with adjustment for possible confounders were also used for associations between serum levels of biomarkers and; (1) severity of RP recorded as the extent of finger blanching calculated with Griffin score, (2) vibration perception thresholds, (3) magnitude of current exposure as [A(8); (m/s
Identifiants
pubmed: 39103464
doi: 10.1038/s41598-024-68846-1
pii: 10.1038/s41598-024-68846-1
doi:
Substances chimiques
Biomarkers
0
von Willebrand Factor
0
Calcitonin Gene-Related Peptide
JHB2QIZ69Z
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
18128Subventions
Organisme : AFA Insurance
ID : 170124
Organisme : AFA Insurance
ID : 170124
Organisme : AFA Insurance
ID : 170124
Organisme : AFA Insurance
ID : 170124
Organisme : AFA Insurance
ID : 170124
Organisme : AFA Insurance
ID : 170124
Organisme : AFA Insurance
ID : 170124
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : Swedish Research Council
ID : 2022-01942
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Organisme : The Swedish Diabetes Foundation
ID : DIA2020-492
Informations de copyright
© 2024. The Author(s).
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