Socio-economic status and head and neck cancer incidence in the Nordic countries.


Journal

International journal of epidemiology
ISSN: 1464-3685
Titre abrégé: Int J Epidemiol
Pays: England
ID NLM: 7802871

Informations de publication

Date de publication:
12 Jun 2024
Historique:
received: 08 12 2023
accepted: 27 07 2024
medline: 12 8 2024
pubmed: 12 8 2024
entrez: 12 8 2024
Statut: ppublish

Résumé

The impact of societal factors on the occurrence of head and neck cancers (HNCs) remains understudied, especially in the Nordic countries. To quantify the association between socio-economic status (SES) and the occurrence of HNCs, this cohort study uses data from the Nordic Occupational Cancer project that combine occupational and cancer registry data from 1961 to 2005 of 14.9 million individuals aged between 30 and 64 years. Occupational categories were combined into seven socio-economic categories. Standardized incidence ratio (SIR) analyses were conducted with the cancer incidence rates for the entire national study populations used as reference rates. Altogether, 83 997 HNCs-72% in men and 28% in women-were recorded. Among men, a gradient of risk associated with SES was observed for cancers of the tongue, other oral cavity subsites, pharynx, oropharynx and larynx in groups with lower SES. Managers showed decreased SIRs of 0.50 to -0.90 also for cancers of the lip, tongue, other oral cavity subsites, oropharynx, nasopharynx, nose and larynx. In contrast, excess risks of tongue, other oral cavity subsites, pharyngeal, oropharyngeal and laryngeal cancers were observed among clerical (SIRs 1.05-1.16), skilled workers (1.04-1.14), unskilled workers (1.16-1.26) and economically inactive men (1.38-1.87). Among women, no risk gradient similar to that in men was revealed. The current study underscores the influence of SES on the incidence of HNCs and highlights the need for targeted interventions, including tobacco and alcohol control policies, and improved access to healthcare services, particularly for socio-economically disadvantaged populations.

Sections du résumé

BACKGROUND BACKGROUND
The impact of societal factors on the occurrence of head and neck cancers (HNCs) remains understudied, especially in the Nordic countries.
METHODS METHODS
To quantify the association between socio-economic status (SES) and the occurrence of HNCs, this cohort study uses data from the Nordic Occupational Cancer project that combine occupational and cancer registry data from 1961 to 2005 of 14.9 million individuals aged between 30 and 64 years. Occupational categories were combined into seven socio-economic categories. Standardized incidence ratio (SIR) analyses were conducted with the cancer incidence rates for the entire national study populations used as reference rates.
RESULTS RESULTS
Altogether, 83 997 HNCs-72% in men and 28% in women-were recorded. Among men, a gradient of risk associated with SES was observed for cancers of the tongue, other oral cavity subsites, pharynx, oropharynx and larynx in groups with lower SES. Managers showed decreased SIRs of 0.50 to -0.90 also for cancers of the lip, tongue, other oral cavity subsites, oropharynx, nasopharynx, nose and larynx. In contrast, excess risks of tongue, other oral cavity subsites, pharyngeal, oropharyngeal and laryngeal cancers were observed among clerical (SIRs 1.05-1.16), skilled workers (1.04-1.14), unskilled workers (1.16-1.26) and economically inactive men (1.38-1.87). Among women, no risk gradient similar to that in men was revealed.
CONCLUSIONS CONCLUSIONS
The current study underscores the influence of SES on the incidence of HNCs and highlights the need for targeted interventions, including tobacco and alcohol control policies, and improved access to healthcare services, particularly for socio-economically disadvantaged populations.

Identifiants

pubmed: 39133936
pii: 7731878
doi: 10.1093/ije/dyae104
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Helsinki University Hospital Research Funding
Organisme : Nordic Cancer Union

Informations de copyright

© The Author(s) 2024; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

Auteurs

Rayan Nikkilä (R)

Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and HUS Helsinki University Hospital, Helsinki, Finland.
Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer and Research, Helsinki, Finland.
Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Päijät-Häme Joint Authority for Health and Wellbeing, Department of Oral and Maxillofacial Surgery, Lahti Central Hospital, Lahti, Finland.

Timo Carpén (T)

Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Palliative Care Unit, Comprehensive Cancer Center, University of Helsinki and HUS Helsinki University Hospital, Helsinki, Finland.

Johnni Hansen (J)

Danish Cancer Institute, Danish Cancer Society, Copenhagen, Denmark.

Sanna Heikkinen (S)

Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer and Research, Helsinki, Finland.

Elsebeth Lynge (E)

Nykøbing Falster Hospital, University of Copenhagen, Nykøbing Falster, Denmark.

Jan Ivar Martinsen (JI)

The Cancer Registry of Norway at the Norwegian Institute of Public Health, Oslo, Norway.

Jenny Selander (J)

Institute of Environmental Medicine, IMM Karolinska Institutet, Stockholm, Sweden.

Ingrid Sivesind Mehlum (IS)

National Institute of Occupational Health (STAMI), Oslo, Norway.
Institute of Health and Society, University of Oslo, Oslo, Norway.
Department of Occupational and Environmental Medicine, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Jóhanna Eyrún Torfadóttir (JE)

Centre of Public Health Sciences, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.

Antti Mäkitie (A)

Department of Otorhinolaryngology-Head and Neck Surgery, University of Helsinki and HUS Helsinki University Hospital, Helsinki, Finland.
Research Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Division of Ear, Nose and Throat Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet and Karolinska Hospital, Stockholm, Sweden.

Eero Pukkala (E)

Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer and Research, Helsinki, Finland.
Health Sciences Unit, Faculty of Social Sciences, Tampere University, Tampere, Finland.

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