The role of FoxA, FiuA, and FpvB in iron acquisition via hydroxamate-type siderophores in Pseudomonas aeruginosa.

Siderophores / metabolism Pseudomonas aeruginosa / metabolism Iron / metabolism Hydroxamic Acids / metabolism Bacterial Proteins / metabolism Biological Transport Ferrichrome / metabolism Membrane Transport Proteins / metabolism Bacterial Outer Membrane Proteins Membrane Proteins Receptors, Cell Surface
Pseudomonas aeruginosa FpvB Hydroxamate siderophores Iron homeostasis Siderophore TonB-dependent transporters

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
13 08 2024
Historique:
received: 13 06 2024
accepted: 01 08 2024
medline: 14 8 2024
pubmed: 14 8 2024
entrez: 13 8 2024
Statut: epublish

Résumé

Siderophores are specialized molecules produced by bacteria and fungi to scavenge iron, a crucial nutrient for growth and metabolism. Catecholate-type siderophores are mainly produced by bacteria, while hydroxamates are mostly from fungi. This study investigates the capacity of nine hydroxamate-type siderophores from fungi and Streptomyces to facilitate iron acquisition by the human pathogen Pseudomonas aeruginosa. Growth assays under iron limitation and

Identifiants

DOI: 10.1038/s41598-024-69152-6 PMID: 39138320
pubmed: 39138320
doi: 10.1038/s41598-024-69152-6
pii: 10.1038/s41598-024-69152-6
doi:

Substances chimiques

Siderophores 0
Iron E1UOL152H7
Hydroxamic Acids 0
Bacterial Proteins 0
FoxA protein, bacteria 0
tonB protein, Bacteria 0
Ferrichrome 15630-64-5
Membrane Transport Proteins 0
Bacterial Outer Membrane Proteins 0
Membrane Proteins 0
Receptors, Cell Surface 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

18795

Subventions

Organisme : Agence Nationale de la Recherche
ID : ANR-22-CE44-0024-01
Organisme : Agence Nationale de la Recherche
ID : ANR-10-IDEX-0002
Organisme : Association Vaincre la Mucoviscidose
ID : RF20230503252
Organisme : Grégory Lemarchal, France
ID : RF20230503252

Informations de copyright

© 2024. The Author(s).

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Auteurs

Virginie Will (V)

CNRS, UMR7242, UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.
UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.

Chloé Frey (C)

CNRS, UMR7242, UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.
UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.

Vincent Normant (V)

CNRS, UMR7242, UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.
UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.

Lauriane Kuhn (L)

Institut de Biologie Moléculaire Et Cellulaire, CNRS, UAR1589, Plateforme Proteomique Strasbourg - Esplanade, 2 Allée Konrad Roentgen, 67084, Strasbourg Cedex, France.

Johana Chicher (J)

Institut de Biologie Moléculaire Et Cellulaire, CNRS, UAR1589, Plateforme Proteomique Strasbourg - Esplanade, 2 Allée Konrad Roentgen, 67084, Strasbourg Cedex, France.

Florian Volck (F)

CNRS, UMR7242, UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.
UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France.

Isabelle J Schalk (IJ)

CNRS, UMR7242, UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France. isabelle.schalk@unistra.fr.
UMR7242, ESBS, University of Strasbourg, Bld Sébastien Brant, 67412, Illkirch, Strasbourg, France. isabelle.schalk@unistra.fr.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents séquestrants › Chélateurs › Agents chélateurs du fer › Sidérophores › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Fer › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Hydroxyacides › Acides hydroxamiques › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Métabolisme › Transport biologique › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Peptides cycliques › Ferrichrome › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de la membrane externe bactérienne › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › The role of FoxA, FiuA, and FpvB in iron...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › The role of FoxA, FiuA, and FpvB in iron...