Association of Cardiac MRI-derived Aortic Stiffness with Early Stages and Progression of Heart Failure with Preserved Ejection Fraction.

Humans Vascular Stiffness / physiology Female Male Heart Failure / physiopathology Aged Stroke Volume / physiology Disease Progression Animals Mice Prospective Studies Magnetic Resonance Imaging, Cine / methods Echocardiography Magnetic Resonance Imaging Pulse Wave Analysis
Animal Studies Aorta Cardiac Heart MR Functional Imaging MR Imaging

Journal

Radiology. Cardiothoracic imaging
ISSN: 2638-6135
Titre abrégé: Radiol Cardiothorac Imaging
Pays: United States
ID NLM: 101748663

Informations de publication

Date de publication:
Aug 2024
Historique:
medline: 15 8 2024
pubmed: 15 8 2024
entrez: 15 8 2024
Statut: ppublish

Résumé

Purpose To investigate if aortic stiffening as detected with cardiac MRI is an early phenomenon in the development and progression of heart failure with preserved ejection fraction (HFpEF). Materials and Methods Both clinical and preclinical studies were performed. The clinical study was a secondary analysis of the prospective HFpEF stress trial (August 2017 through September 2019) and included 48 participants (median age, 69 years [range, 65-73 years]; 33 female, 15 male) with noncardiac dyspnea (NCD,

Identifiants

DOI: 10.1148/ryct.230344 PMID: 39145733
pubmed: 39145733
doi: 10.1148/ryct.230344
doi:

Banques de données

ClinicalTrials.gov
['NCT03260621']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e230344

Auteurs

Alexander Schulz (A)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0000-0001-5589-8792

Isabel N Schellinger (IN)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).

Sören J Backhaus (SJ)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).

Ansgar S Adler (AS)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0009-0008-0682-0719

Torben Lange (T)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0000-0003-0505-2582

Ruben Evertz (R)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0000-0002-5904-4652

Johannes T Kowallick (JT)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0000-0002-3580-619X

Annett Hoffmann (A)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).

Christian Matek (C)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0000-0001-8528-8581

Philip S Tsao (PS)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).

Gerd Hasenfuß (G)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).

Uwe Raaz (U)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).

Andreas Schuster (A)

From the Department of Medicine, Cardiovascular Division, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (A. Schulz); Department of Cardiology and Pneumology, University Medical Center Göttingen, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (A. Schulz, I.N.S., S.J.B., T.L., R.E., G.H., U.R., A. Schuster); School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom (S.J.B., A. Schuster); Institute of Biomedical Imaging, University of Graz, Graz, Austria (A.S.A.); FORUM Radiology, Rosdorf, Germany (J.T.K.); German Center for Cardiovascular Research (DZHK), Partner Site Lower Saxony, Germany (J.T.K.); Department of General, Visceral, Transplant, Vascular and Pediatric Surgery, University Hospital Würzburg, Würzburg, Germany (A.H.); Institute of Pathology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany (C.M.); Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (P.S.T.); VA Palo Alto Health Care System, Palo Alto, Calif (P.S.T.); and FORUM Cardiology, Rosdorf, Germany (A. Schuster).
ORCID: 0000-0003-1508-1125

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Rigidité vasculaire › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Défaillance cardiaque › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Débit cardiaque › Débit systolique › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Évolution de la maladie › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Eucaryotes › Animaux › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › IRM dynamique › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Échocardiographie › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Association of Cardiac MRI-derived Aortic...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Analyse de l'onde de pouls › Association of Cardiac MRI-derived Aortic...