Atypical carcinoid tumour of the larynx.


Journal

BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291

Informations de publication

Date de publication:
24 Aug 2024
Historique:
medline: 26 8 2024
pubmed: 26 8 2024
entrez: 24 8 2024
Statut: epublish

Résumé

A man in his 80s with long-standing left-sided throat discomfort presented with hypophonia and odynophagia. A flexible nasoendoscopy revealed a supraglottic mass in the left arytenoid. An urgent microlaryngoscopy and biopsy demonstrated a supraglottic laryngeal tumour consistent with atypical carcinoid on histopathological examination. Head and neck multidisciplinary team discussions led to the selection of ablative carbon dioxide laser therapy as primary treatment. Two years later, there was local recurrence, prompting a second laser resection and selective neck dissection. Further laser resection was performed 3 years later for another recurrence. Despite an initial encouraging response with local control, 4 years after the initial treatment, there was substantial progression with multiple cutaneous and subcutaneous metastases and further local recurrence soon after. Palliative radiotherapy to the cutaneous metastases provided partial benefit, transitioning to best supportive care. He died 10 years after the initial onset of symptoms, primarily due to cancer progression.

Identifiants

pubmed: 39181571
pii: 17/8/e257299
doi: 10.1136/bcr-2023-257299
pii:
doi:

Types de publication

Journal Article Case Reports

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© BMJ Publishing Group Limited 2024. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Vaishnevy Ganesh (V)

ENT, NHS Tayside, Dundee, UK vaishnevy.ganesh@nhs.scot.

Kathryn McPherson (K)

Pathology, NHS Tayside, Dundee, UK.

Andrew Affleck (A)

Dermatology, NHS Tayside, Dundee, UK.

Jaiganesh Manickavasagam (J)

ENT, Ninewells Hospital and Medical School, Dundee, UK.

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