Pancreatic cancer
dose-averaged LET
scanned carbon-ion radiotherapy
simultaneous integrated boost
tumor control probability
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
Sep 2024
Sep 2024
Historique:
received:
13
05
2024
revised:
21
06
2024
accepted:
11
07
2024
medline:
31
8
2024
pubmed:
31
8
2024
entrez:
28
8
2024
Statut:
ppublish
Résumé
Carbon-ion radiotherapy (CiRT) has been used for the treatment of locally advanced pancreatic cancer (LAPC) with uniform dose plan. The aim of the present study is to investigate the effectiveness of a simultaneous integrated boost (SIB) technique with scanned CiRT against LAPC. Data of 21 patients with LAPC were used to compare two treatment planning approaches: a conventional uniform dose approach and a SIB approach. A relative biological effectiveness (RBE)-weighted dose (D The HR-PTV D The SIB approach effectively increased the RBE-weighted dose and LET
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
Carbon-ion radiotherapy (CiRT) has been used for the treatment of locally advanced pancreatic cancer (LAPC) with uniform dose plan. The aim of the present study is to investigate the effectiveness of a simultaneous integrated boost (SIB) technique with scanned CiRT against LAPC.
MATERIALS AND METHODS
METHODS
Data of 21 patients with LAPC were used to compare two treatment planning approaches: a conventional uniform dose approach and a SIB approach. A relative biological effectiveness (RBE)-weighted dose (D
RESULTS
RESULTS
The HR-PTV D
CONCLUSION
CONCLUSIONS
The SIB approach effectively increased the RBE-weighted dose and LET
Identifiants
pubmed: 39197905
pii: 44/9/3821
doi: 10.21873/anticanres.17208
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3821-3828Informations de copyright
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.