Evaluation of the Antidiabetic Potential of Xanthone-Rich Extracts from
Gentiana
/ chemistry
Xanthones
/ pharmacology
Hypoglycemic Agents
/ pharmacology
Animals
Plant Extracts
/ pharmacology
Rats
Rats, Wistar
Male
Glycoside Hydrolase Inhibitors
/ pharmacology
Blood Glucose
/ drug effects
alpha-Glucosidases
/ metabolism
Chromatography, High Pressure Liquid
Diabetes Mellitus, Experimental
/ drug therapy
Plant Roots
/ chemistry
Gentiana dinarica
Gentiana utriculosa
antidiabetic properties
decussatin
decussatin-1-O-primeveroside
diabetes
norswertianin
norswertianin-1-O-primeveroside
xanthones
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
21 Aug 2024
21 Aug 2024
Historique:
received:
18
07
2024
revised:
16
08
2024
accepted:
18
08
2024
medline:
1
9
2024
pubmed:
31
8
2024
entrez:
29
8
2024
Statut:
epublish
Résumé
Despite the existence of various therapeutic approaches, diabetes mellitus and its complications have been an increasing burden of mortality and disability globally. Hence, it is necessary to evaluate the efficacy and safety of medicinal plants to support existing drugs in treating diabetes. Xanthones, the main secondary metabolites found in
Identifiants
pubmed: 39201752
pii: ijms25169066
doi: 10.3390/ijms25169066
pii:
doi:
Substances chimiques
Xanthones
0
Hypoglycemic Agents
0
Plant Extracts
0
Glycoside Hydrolase Inhibitors
0
Blood Glucose
0
xanthone
9749WEV0CA
alpha-Glucosidases
EC 3.2.1.20
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministry of Science Technological Development and Innovation of the Republic of Serbia
ID : 451-03-66/2024-03/200007