From admission to discharge: a systematic review of clinical natural language processing along the patient journey.
Bias
Clinical natural language processing
Explainable ML
Out-of-distribution generalization
Patient journey
Journal
BMC medical informatics and decision making
ISSN: 1472-6947
Titre abrégé: BMC Med Inform Decis Mak
Pays: England
ID NLM: 101088682
Informations de publication
Date de publication:
29 Aug 2024
29 Aug 2024
Historique:
received:
22
12
2023
accepted:
20
08
2024
medline:
31
8
2024
pubmed:
31
8
2024
entrez:
29
8
2024
Statut:
epublish
Résumé
Medical text, as part of an electronic health record, is an essential information source in healthcare. Although natural language processing (NLP) techniques for medical text are developing fast, successful transfer into clinical practice has been rare. Especially the hospital domain offers great potential while facing several challenges including many documents per patient, multiple departments and complex interrelated processes. In this work, we survey relevant literature to identify and classify approaches which exploit NLP in the clinical context. Our contribution involves a systematic mapping of related research onto a prototypical patient journey in the hospital, along which medical documents are created, processed and consumed by hospital staff and patients themselves. Specifically, we reviewed which dataset types, dataset languages, model architectures and tasks are researched in current clinical NLP research. Additionally, we extract and analyze major obstacles during development and implementation. We discuss options to address them and argue for a focus on bias mitigation and model explainability. While a patient's hospital journey produces a significant amount of structured and unstructured documents, certain steps and documents receive more research attention than others. Diagnosis, Admission and Discharge are clinical patient steps that are researched often across the surveyed paper. In contrast, our findings reveal significant under-researched areas such as Treatment, Billing, After Care, and Smart Home. Leveraging NLP in these stages can greatly enhance clinical decision-making and patient outcomes. Additionally, clinical NLP models are mostly based on radiology reports, discharge letters and admission notes, even though we have shown that many other documents are produced throughout the patient journey. There is a significant opportunity in analyzing a wider range of medical documents produced throughout the patient journey to improve the applicability and impact of NLP in healthcare. Our findings suggest that there is a significant opportunity to leverage NLP approaches to advance clinical decision-making systems, as there remains a considerable understudied potential for the analysis of patient journey data.
Sections du résumé
BACKGROUND
BACKGROUND
Medical text, as part of an electronic health record, is an essential information source in healthcare. Although natural language processing (NLP) techniques for medical text are developing fast, successful transfer into clinical practice has been rare. Especially the hospital domain offers great potential while facing several challenges including many documents per patient, multiple departments and complex interrelated processes.
METHODS
METHODS
In this work, we survey relevant literature to identify and classify approaches which exploit NLP in the clinical context. Our contribution involves a systematic mapping of related research onto a prototypical patient journey in the hospital, along which medical documents are created, processed and consumed by hospital staff and patients themselves. Specifically, we reviewed which dataset types, dataset languages, model architectures and tasks are researched in current clinical NLP research. Additionally, we extract and analyze major obstacles during development and implementation. We discuss options to address them and argue for a focus on bias mitigation and model explainability.
RESULTS
RESULTS
While a patient's hospital journey produces a significant amount of structured and unstructured documents, certain steps and documents receive more research attention than others. Diagnosis, Admission and Discharge are clinical patient steps that are researched often across the surveyed paper. In contrast, our findings reveal significant under-researched areas such as Treatment, Billing, After Care, and Smart Home. Leveraging NLP in these stages can greatly enhance clinical decision-making and patient outcomes. Additionally, clinical NLP models are mostly based on radiology reports, discharge letters and admission notes, even though we have shown that many other documents are produced throughout the patient journey. There is a significant opportunity in analyzing a wider range of medical documents produced throughout the patient journey to improve the applicability and impact of NLP in healthcare.
CONCLUSIONS
CONCLUSIONS
Our findings suggest that there is a significant opportunity to leverage NLP approaches to advance clinical decision-making systems, as there remains a considerable understudied potential for the analysis of patient journey data.
Identifiants
pubmed: 39210370
doi: 10.1186/s12911-024-02641-w
pii: 10.1186/s12911-024-02641-w
pmc: PMC11360876
doi:
Types de publication
Journal Article
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
238Subventions
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Organisme : Ministry for Economic Affairs, Industry, Climate Action and Energy of the State of North-Rhine-Westphalia, Germany
ID : 5-2011-0041/2
Informations de copyright
© 2024. The Author(s).
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