Evolution of a bistable genetic system in fluctuating and nonfluctuating environments.

Salmonella enterica / genetics Epigenesis, Genetic Operon / genetics Environment Phenotype Evolution, Molecular Biological Evolution Bacteriophages / genetics Models, Genetic Mutation Gene Expression Regulation, Bacterial
adaptative strategies bacterial experimental evolution epigenetic switch fluctuating environments phage-bacteria interactions

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
03 Sep 2024
Historique:
medline: 31 8 2024
pubmed: 31 8 2024
entrez: 30 8 2024
Statut: ppublish

Résumé

Epigenetic mechanisms can generate bacterial lineages capable of spontaneously switching between distinct phenotypes. Currently, mathematical models and simulations propose epigenetic switches as a mechanism of adaptation to deal with fluctuating environments. However, bacterial evolution experiments for testing these predictions are lacking. Here, we exploit an epigenetic switch in

Identifiants

DOI: 10.1073/pnas.2322371121 PMID: 39213178
pubmed: 39213178
doi: 10.1073/pnas.2322371121
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2322371121

Subventions

Organisme : HHS | NIH | National Institute of General Medical Sciences (NIGMS)
ID : R35GM148351
Organisme : Ministerio de Ciencia e Innovación (MCIN)
ID : BIO2016-75235
Organisme : Ministerio de Ciencia, Innovación y Universidades (MCIU)
ID : PID2020-116995RB-I00
Organisme : NIGMS NIH HHS
ID : R35 GM148351
Pays : United States
Organisme : Ministerio de Ciencia, Innovación y Universidades (MCIU)
ID : CNS2022-135641

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Rocío Fernández-Fernández (R)

Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Sevilla, Sevilla 41012, Spain.
ORCID: 0000-0002-9714-980X

David R Olivenza (DR)

Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla 41012, Spain.

Esther Weyer (E)

Department of Electrical and Computer Engineering, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19716.
Department of Biomedical Engineering, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19716.

Abhyudai Singh (A)

Department of Electrical and Computer Engineering, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19716.
Department of Biomedical Engineering, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19716.
ORCID: 0000-0002-1451-2838

Josep Casadesús (J)

Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Sevilla 41012, Spain.
ORCID: 0000-0002-2308-293X

María Antonia Sánchez-Romero (M)

Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Sevilla, Sevilla 41012, Spain.
ORCID: 0000-0003-3098-1033

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Classifications MeSH

questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Salmonella › Salmonella enterica › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Génome microbien › Génome bactérien › Opéron › Evolution of a bistable genetic system in...
questionsmedicales.fr › Environnement et santé publique › Environnement › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes biologiques › Évolution biologique › Évolution moléculaire › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes biologiques › Évolution biologique › Evolution of a bistable genetic system in...
questionsmedicales.fr › Virus › Bactériophages › Evolution of a bistable genetic system in...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles génétiques › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Evolution of a bistable genetic system in...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes bactériens › Evolution of a bistable genetic system in...