The efficiency of two different synthetic bone graft materials on alveolar ridge preservation after tooth extraction: a split-mouth study.
Humans
Tooth Extraction
Tooth Socket
/ surgery
Alveolar Bone Loss
/ prevention & control
Bone Substitutes
/ therapeutic use
Polylactic Acid-Polyglycolic Acid Copolymer
/ therapeutic use
Male
Female
Lactic Acid
/ therapeutic use
Adult
Polyglycolic Acid
/ therapeutic use
Alveolar Process
/ pathology
Molar, Third
/ surgery
Tooth, Impacted
/ surgery
Follow-Up Studies
Young Adult
Surgical Flaps
Biocompatible Materials
/ therapeutic use
Alveolar Ridge Augmentation
/ methods
Hydroxyapatites
/ therapeutic use
Mandible
/ surgery
Calcium Phosphates
/ therapeutic use
Treatment Outcome
Dental socket preservation
HA/β-TCP
PLGA
Periodontal bone loss
Teeth removal
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
04 Sep 2024
04 Sep 2024
Historique:
received:
04
06
2024
accepted:
23
08
2024
medline:
5
9
2024
pubmed:
5
9
2024
entrez:
4
9
2024
Statut:
epublish
Résumé
Alveolar Bone loss occurs frequently during the first six months after tooth extraction. Various studies have proposed different methods to reduce as much as possible the atrophy of the alveolar ridge after tooth extraction. Filling the socket with biomaterials after extraction can reduce the resorption of the alveolar ridge. We compared the height of the alveolar process at the mesial and distal aspects of the extraction site and the resorption rate was calculated after the application of HA/β-TCP or synthetic co-polymer polyglycolic - polylactic acid PLGA mixed with blood to prevent socket resorption immediately and after tooth extraction. The study was conducted on 24 extraction sockets of impacted mandibular third molars bilaterally, vertically, and completely covered, with a thin bony layer. HA/β-TCP was inserted into 12 of the dental sockets immediately after extraction, and the synthetic polymer PLGA was inserted into 12 of the dental sockets. All sockets were covered completely with a full-thickness envelope flap. Follow-up was performed for one year after extraction, using radiographs and stents for the vertical alveolar ridge measurements. The mean resorption rate in the HA/β-TCP and PLGA groups was ± 1.23 mm and ± 0.1 mm, respectively. A minimal alveolar bone height reduction of HA/β-TCP was observed after 9 months, the reduction showed a slight decrease to 0.93 mm, while this rate was 0.04 mm after 9 months in the PLGA group. Moreover, the bone height was maintained after three months, indicating a good HA/β-TCP graft performance in preserving alveolar bone (1.04 mm) while this rate was (0.04 mm) for PLGA. The PLGA graft demonstrated adequate safety and efficacy in dental socket preservation following tooth extraction. However, HA/β-TCP causes greater resorption at augmented sites than PLGA, which clinicians should consider during treatment planning.
Sections du résumé
BACKGROUND
BACKGROUND
Alveolar Bone loss occurs frequently during the first six months after tooth extraction. Various studies have proposed different methods to reduce as much as possible the atrophy of the alveolar ridge after tooth extraction. Filling the socket with biomaterials after extraction can reduce the resorption of the alveolar ridge. We compared the height of the alveolar process at the mesial and distal aspects of the extraction site and the resorption rate was calculated after the application of HA/β-TCP or synthetic co-polymer polyglycolic - polylactic acid PLGA mixed with blood to prevent socket resorption immediately and after tooth extraction.
METHODS
METHODS
The study was conducted on 24 extraction sockets of impacted mandibular third molars bilaterally, vertically, and completely covered, with a thin bony layer. HA/β-TCP was inserted into 12 of the dental sockets immediately after extraction, and the synthetic polymer PLGA was inserted into 12 of the dental sockets. All sockets were covered completely with a full-thickness envelope flap. Follow-up was performed for one year after extraction, using radiographs and stents for the vertical alveolar ridge measurements.
RESULTS
RESULTS
The mean resorption rate in the HA/β-TCP and PLGA groups was ± 1.23 mm and ± 0.1 mm, respectively. A minimal alveolar bone height reduction of HA/β-TCP was observed after 9 months, the reduction showed a slight decrease to 0.93 mm, while this rate was 0.04 mm after 9 months in the PLGA group. Moreover, the bone height was maintained after three months, indicating a good HA/β-TCP graft performance in preserving alveolar bone (1.04 mm) while this rate was (0.04 mm) for PLGA.
CONCLUSION
CONCLUSIONS
The PLGA graft demonstrated adequate safety and efficacy in dental socket preservation following tooth extraction. However, HA/β-TCP causes greater resorption at augmented sites than PLGA, which clinicians should consider during treatment planning.
Identifiants
pubmed: 39232718
doi: 10.1186/s12903-024-04803-8
pii: 10.1186/s12903-024-04803-8
doi:
Substances chimiques
Bone Substitutes
0
Polylactic Acid-Polyglycolic Acid Copolymer
1SIA8062RS
Lactic Acid
33X04XA5AT
Polyglycolic Acid
26009-03-0
hydroxyapatite-beta tricalcium phosphate
0
Biocompatible Materials
0
Hydroxyapatites
0
Calcium Phosphates
0
Types de publication
Journal Article
Comparative Study
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1040Informations de copyright
© 2024. The Author(s).
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