Case Report: A Case Report on an 18-Year-Old Female with Cerebral Vasculitis in Systemic Lupus Erythematosus (SLE).

cerebral vasculitis immunological dysfunction multiorgan failure neurological complications systemic lupus erythematosus (SLE) treatment challenges

Journal

F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320

Informations de publication

Date de publication:
2024
Historique:
accepted: 05 06 2024
medline: 5 9 2024
pubmed: 5 9 2024
entrez: 5 9 2024
Statut: epublish

Résumé

Cerebral vasculitis is a rare but severe complication of Systemic Lupus Erythematosus (SLE), presenting significant challenges in management due to its potential for devastating neurological consequences and poor prognosis. We present a case of an 18-year-old female with known SLE who presented with seizures, declining cognitive function, and unresponsiveness. Neurological examination, laboratory investigations, and radiological imaging supported the diagnosis of cerebral vasculitis secondary to SLE. Despite aggressive immunosuppressive therapy, the patient's neurological status continued to deteriorate, leading to respiratory failure and multiorgan dysfunction. Ultimately, the patient succumbed to multiorgan failure attributed to severe CNS vasculitis and its complications. This case underscores the importance of early recognition and aggressive management of cerebral vasculitis in SLE while highlighting the need for further research into more effective therapeutic strategies to improve patient outcomes.

Identifiants

pubmed: 39233782
doi: 10.12688/f1000research.152704.1
pmc: PMC11372350
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

614

Informations de copyright

Copyright: © 2024 Dudhe S et al.

Déclaration de conflit d'intérêts

No competing interests were disclosed.

Auteurs

Sakshi Dudhe (S)

Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

Gaurav V Mishra (GV)

Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

Pratap Singh Parihar (PS)

Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

Devyansh Nimodia (D)

Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

Dhananjay Shinde (D)

Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

Anjali Kumari (A)

Department of Radio-Diagnosis,, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

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