Unveiling the solution structure of a DNA duplex with continuous silver-modified Watson-Crick base pairs.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
05 Sep 2024
05 Sep 2024
Historique:
received:
21
12
2023
accepted:
20
08
2024
medline:
6
9
2024
pubmed:
6
9
2024
entrez:
5
9
2024
Statut:
epublish
Résumé
The challenge of transforming organized DNA structures into their metallized counterparts persists in the scientific field. In this context, utilizing DNA molecules modified with 7-deazapurine, provides a transformative solution. In this study, we present the solution structure of a DNA duplex that can be transformed into its metallized equivalent while retaining the natural base pairing arrangement through the creation of silver-modified Watson-Crick base pairs. Unlike previously documented X-ray structures, our research demonstrates the feasibility of preserving the intrinsic DNA self-assembly while incorporating Ag
Identifiants
pubmed: 39237564
doi: 10.1038/s41467-024-51876-8
pii: 10.1038/s41467-024-51876-8
doi:
Substances chimiques
Silver
3M4G523W1G
DNA
9007-49-2
Solutions
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
7763Informations de copyright
© 2024. The Author(s).
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