RNA dynamics from experimental and computational approaches.

Nucleic Acid Conformation RNA / metabolism Molecular Dynamics Simulation Computational Biology / methods Humans

Journal

Structure (London, England : 1993)
ISSN: 1878-4186
Titre abrégé: Structure
Pays: United States
ID NLM: 101087697

Informations de publication

Date de publication:
05 Sep 2024
Historique:
received: 05 04 2024
revised: 21 06 2024
accepted: 29 07 2024
medline: 7 9 2024
pubmed: 7 9 2024
entrez: 6 9 2024
Statut: ppublish

Résumé

Conformational dynamics is crucial for the biological function of RNA molecules and for their potential as therapeutic targets. This meeting report outlines key "take-home" messages that emerged from the presentations and discussions during the CECAM workshop "RNA dynamics from experimental and computational approaches" in Paris, June 26-28, 2023.

Identifiants

DOI: 10.1016/j.str.2024.07.019 PMID: 39241758
pubmed: 39241758
pii: S0969-2126(24)00282-X
doi: 10.1016/j.str.2024.07.019
pii:
doi:

Substances chimiques

RNA 63231-63-0

Types de publication

Journal Article Congress Clinical Conference

Langues

eng

Sous-ensembles de citation

IM

Pagination

1281-1287

Informations de copyright

Copyright © 2024.

Déclaration de conflit d'intérêts

Declaration of interests P.G. and Y.F. are or were Sanofi employees and may own stocks in Sanofi.

Auteurs

Giovanni Bussi (G)

Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, 34136 Trieste, Italy. Electronic address: bussi@sissa.it.

Massimiliano Bonomi (M)

Institut Pasteur, Université Paris Cité, CNRS UMR 3528, Computational Structural Biology Unit, Paris, France. Electronic address: mbonomi@pasteur.fr.

Paraskevi Gkeka (P)

Integrated Drug Discovery, Molecular Design Sciences, Sanofi, Vitry-sur-Seine, France. Electronic address: paraskevi.gkeka@sanofi.com.

Michael Sattler (M)

Technical University of Munich, Munich, Germany; Helmholtz Munich, Munich, Germany. Electronic address: michael.sattler@helmholtz-munich.de.

Hashim M Al-Hashimi (HM)

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Pascal Auffinger (P)

Université de Strasbourg, Architecture et Réactivité de l'ARN, Institut de Biologie Moléculaire et Cellulaire du CNRS, 2 Allée Konrad Roentgen, 67084 Strasbourg, France.

Maria Duca (M)

Université Côte d'Azur, CNRS, Institute of Chemistry of Nice, Nice, France.

Yann Foricher (Y)

Integrated Drug Discovery, Small Molecules Medicinal Chemistry, Sanofi, Vitry-sur-Seine, France.

Danny Incarnato (D)

Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, the Netherlands.

Alisha N Jones (AN)

Department of Chemistry, New York University, New York, NY, USA.

Serdal Kirmizialtin (S)

Department of Chemistry, New York University, New York, NY, USA; Chemistry Program, Science Division, New York University, Abu Dhabi, United Arab Emirates.

Miroslav Krepl (M)

Institute of Biophysics of the Czech Academy of Sciences, Kralovopolska 135, Brno 612 00, Czech Republic.

Modesto Orozco (M)

Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, and Department of Biochemistry and Biomedicine, University of Barcelona, Barcelona, Spain.

Giulia Palermo (G)

Department of Bioengineering and Department of Chemistry, The University of California, Riverside, Riverside, CA, USA.

Samuela Pasquali (S)

Laboratoire Biologie Fonctionnelle et Adaptative, CNRS UMR 8251 INSERM ERL 1133, Université Paris Cité, 35 rue Hélène Brion, 75013 Paris, France.

Loïc Salmon (L)

Centre de RMN à Très Hauts Champs, UMR 5082 (CNRS, École Normale Supérieure de Lyon, Université Claude Bernard Lyon 1), University of Lyon, 69100 Villeurbanne, France.

Harald Schwalbe (H)

Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, 60438 Frankfurt/Main, Germany.

Eric Westhof (E)

Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de biologie moléculaire et cellulaire du CNRS, 67084 Strasbourg, France.

Martin Zacharias (M)

Physics Department and Center of Protein Assemblies, Technical University of Munich, Munich, Germany.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › RNA dynamics from experimental and...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › RNA dynamics from experimental and...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › RNA dynamics from experimental and...
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › RNA dynamics from experimental and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › RNA dynamics from experimental and...