The Impact of Body Mass Index on the Mortality of Myocardial Infarction Patients With Nonobstructive Coronary Arteries.
Humans
Male
Female
Body Mass Index
Middle Aged
Hospital Mortality
Risk Factors
Myocardial Infarction
/ mortality
Retrospective Studies
Prognosis
Follow-Up Studies
Aged
Time Factors
Risk Assessment
/ methods
Coronary Artery Disease
/ mortality
Survival Rate
/ trends
Coronary Vessels
/ diagnostic imaging
Coronary Angiography
MINOCA
/ complications
adverse events
mortality
myocardial infarction
obesity
overweight
Journal
Clinical cardiology
ISSN: 1932-8737
Titre abrégé: Clin Cardiol
Pays: United States
ID NLM: 7903272
Informations de publication
Date de publication:
Sep 2024
Sep 2024
Historique:
revised:
08
08
2024
received:
29
04
2024
accepted:
19
08
2024
medline:
12
9
2024
pubmed:
12
9
2024
entrez:
12
9
2024
Statut:
ppublish
Résumé
Myocardial infarction without significant stenosis or occlusion of the coronary arteries carries a high risk of recurrent major adverse cardiovascular events and poor prognosis. This study aimed to investigate the association between body mass index and outcomes in patients with a suspected myocardial infarction with nonobstructive coronary artery disease (MINOCA). Patients were recruited at Bergmannsheil University Hospital from January 2010 to April 2021. The primary outcomes were in-hospital and long-term mortality. Secondary outcomes consisted of adverse events during hospitalization and during follow-up. A total of 373 patients were included in the study, with a mean follow-up time of 6.2 years. The patients were divided into different BMI groups: < 25 kg/m² (n = 121), 25-30 kg/m² (n = 140), and > 30 kg/m² (n = 112). In-hospital mortality was 1.7% versus 2.1% versus 4.5% (p = 0.368). However, long-term mortality tended to be higher in the < 25 kg/m² group compared to the 25-30 and > 30 kg/m² groups (log-rank p = 0.067). Subgroup analysis using Kaplan-Meier analysis showed a higher rate of cardiac cause of death in the < 25 kg/m² group compared to the 25-30 and > 30 kg/m² groups: 5.7% versus 1.1% versus 0.0% (log-rank p = 0.042). No significant differences were observed in other adverse events between the different BMI groups during hospitalization and long-term follow-up. Patients with a BMI < 25 kg/m² who experience a suspected myocardial infarction without significant coronary artery disease may have higher all-cause mortality and cardiovascular cause of death. However, further data are needed to confirm these findings.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e70013Subventions
Organisme : InnovationForum program of the Medical Faculty, RUB (Grants IF-023-22 and IF-034-22) EU's Horizon 2020 research and innovation program (Grant 739593) Deutsche Forschungsgemeinschaft (Grants HA 7512/2-1 and HA 7512/2-4) Else-Kröner-foundation (Grant 2022_EKES.48) German Heart Foundation (Grant 2024).
Informations de copyright
© 2024 The Author(s). Clinical Cardiology published by Wiley Periodicals, LLC.
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