Expansion of tumor-reactive CD8

CD8-Positive T-Lymphocytes / immunology Immune Checkpoint Inhibitors / therapeutic use Spleen / immunology Humans Animals Mice Female Mice, Inbred C57BL Male Cell Differentiation / immunology Neoplasms / immunology

Journal

Science immunology
ISSN: 2470-9468
Titre abrégé: Sci Immunol
Pays: United States
ID NLM: 101688624

Informations de publication

Date de publication:
13 Sep 2024
Historique:
medline: 13 9 2024
pubmed: 13 9 2024
entrez: 13 9 2024
Statut: ppublish

Résumé

Immune checkpoint blockade (ICB) enhances T cell responses against cancer, leading to long-term survival in a fraction of patients. CD8

Identifiants

DOI: 10.1126/sciimmunol.adi3487 PMID: 39270006
pubmed: 39270006
doi: 10.1126/sciimmunol.adi3487
doi:

Substances chimiques

Immune Checkpoint Inhibitors 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadi3487

Auteurs

Duncan M Morgan (DM)

Department of Chemical Engineering, MIT, Cambridge, MA 02139, USA.
Koch Institute at MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0002-3253-1362

Brendan L Horton (BL)

Koch Institute at MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0002-9551-9002

Vidit Bhandarkar (V)

Koch Institute at MIT, Cambridge, MA 02139, USA.
Department of Biology, MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0002-6526-4360

Richard Van (R)

Koch Institute at MIT, Cambridge, MA 02139, USA.
Department of Biology, MIT, Cambridge, MA 02139, USA.

Teresa Dinter (T)

Koch Institute at MIT, Cambridge, MA 02139, USA.
Department of Biology, MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0003-4764-501X

Maria Zagorulya (M)

Koch Institute at MIT, Cambridge, MA 02139, USA.
Department of Biology, MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0002-4478-5378

J Christopher Love (JC)

Department of Chemical Engineering, MIT, Cambridge, MA 02139, USA.
Koch Institute at MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0003-0921-3144

Stefani Spranger (S)

Koch Institute at MIT, Cambridge, MA 02139, USA.
Department of Biology, MIT, Cambridge, MA 02139, USA.
ORCID: 0000-0003-3257-4546

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Classifications MeSH

questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD8+ › Expansion of tumor-reactive CD8
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antinéoplasiques › Antinéoplasiques immunologiques › Inhibiteurs de points de contrôle immunitaires › Expansion of tumor-reactive CD8
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système lymphatique › Tissu lymphoïde › Rate › Expansion of tumor-reactive CD8
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Expansion of tumor-reactive CD8
questionsmedicales.fr › Eucaryotes › Animaux › Expansion of tumor-reactive CD8
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Expansion of tumor-reactive CD8
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Expansion of tumor-reactive CD8
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Expansion of tumor-reactive CD8
questionsmedicales.fr › Tumeurs › Expansion of tumor-reactive CD8