Brain abscesses: the first report of disseminated Nocardia beijingensis infection in an immunocompetent individual in China.
Nocardia beijingensis (N. beijingensis)
Brain abscess
Immunocompetent
Infection
Phylogenetic tree
Journal
BMC neurology
ISSN: 1471-2377
Titre abrégé: BMC Neurol
Pays: England
ID NLM: 100968555
Informations de publication
Date de publication:
13 Sep 2024
13 Sep 2024
Historique:
received:
20
02
2024
accepted:
26
08
2024
medline:
14
9
2024
pubmed:
14
9
2024
entrez:
13
9
2024
Statut:
epublish
Résumé
Nocardia is widely distributed in the natural environment and typically cause opportunistic infections. However, it is important to note that the pathogenicity of different Nocardia species may vary significantly. Here we reported the first case of brain abscess caused by Nocardia beijingensis (N. beijingensis) infection in China. A 70-year-old male immunocompetent individual came to our hospital for treatment due to headache. After examination, it was found that he had a brain abscess caused by N. beijingensis. By utilizing a combination of surgical intervention and antibiotic therapy, the patient ultimately achieved full recovery. In addition, we isolated this strain and displayed its ultrastructure through scanning electron microscopy. The phylogenetic tree was analyzed by 16 S rRNA sequence. A literature review of N. beijingensis infections in all immunocompetent and immunocompromised patients was presented. It highlighted that abscess formation appears to be a common manifestation of N. beijingensis infection, and N. beijingensis has become an emerging pathogen in immunocompetent individuals.
Identifiants
pubmed: 39272012
doi: 10.1186/s12883-024-03826-6
pii: 10.1186/s12883-024-03826-6
doi:
Substances chimiques
Anti-Bacterial Agents
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
341Subventions
Organisme : New Project of Zhejiang Provincial People's Hospital entitled "Construction of Rapid Nucleic Acid Detection Platform for Invasive Fungi"
ID : 20211214
Informations de copyright
© 2024. The Author(s).
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